223776-72-5

Upstream product

• 73341-11-4 Trimethyl-((Z)-1-phenethyl-hexa-1,5-dienyloxy)-silane 
• 7766-48-5 1-iodo-4-pentene 
• 645-59-0 dihydrocinnamonitrile 
• 122334-35-4 N-methoxy-N-methyl-hex-5-enamide 
• 103-63-9 1-phenyl-2-bromoethane 
• 73341-07-8 2,6-diphenyl-4-trimethylsiloxy-2,3-hexadiene 
• 61157-31-1 3-phenylpropionyltrimethylsilane 

Downstream Products

• 200191-38-4 5-oxo-7-phenylheptanal 

Relevant academic research and scientific papers

Photochemical transformation of γ,δ-unsaturated ketone O-(p-cyanophenyl)oximes to 3,4-dihydro-2H-pyrrole derivatives

γ,δ-Unsaturated ketone O-(p-cyanophenyl)oximes are transformed to 3,4-dihydro-2H-pyrroles by the photosensitized electron transfer process.

Stereoselection in Intramolecular Diels-Alder Reactions of 2-Cyano-1-azadienes: Indolizidine and Quinolizidine Synthesis

Progress toward understanding the scope and diastereoselectivity of intramolecular Diels-Alder reactions using 2-cyano-1-azadienes is described herein. The resulting cyanoenamine products are underutilized intermediates in organic synthesis. Assembly of the Diels-Alder precursors was achieved using an improved imine condensation/oxidative cyanation protocol. By this method, several highly substituted indolizidine and quinolizidine architectures were constructed. Quantum mechanical DFT calculations at the B3LYP/6-31+G(d) level of theory were performed for these cyclizations and provide insights into the origins of the observed diastereoselectivities.

Barbier-type reactions of nitriles and alkyl iodides mediated by samarium(II) iodide in the presence of catalytic nickel(II) iodide

The samarium(II) iodide-mediated intermolecular Barbier-type reactions of nitriles and alkyl iodides have been investigated. In the presence of a catalytic amount of nickel(II) iodide, the reaction proceeded smoothly to provide the corresponding ketones. Amides also reacted to give ketones under the same Barbier-type conditions. (C) 2000 Elsevier Science Ltd.