22382-94-1Relevant articles and documents
Cobalt-catalyzed addition of styrylboronic acids to 2-vinylpyridine derivatives
Kobayashi, Tsuneyuki,Yorimitsu, Hideki,Oshima, Koichiro
supporting information; experimental part, p. 669 - 673 (2011/10/09)
Treatment of 2-vinyl nitrogen-containing heteroaromatic compounds with styrylboronic acid in the presence of a cobalt catalyst and a base results in an addition reaction to afford the corresponding 4-phenyl-3-butenyl heteroarenes. The adjacent nitrogen atom is essential for the promotion of the reaction because the nitrogen accelerates the addition of the styryl cobalt species, generated by transmetalation, onto the vinyl group. The reaction represents a rare example of cobalt catalysis in the reactions of organoboronic acids. Accelerated addition: Treatment of 2-vinylpyridine derivatives with styrylboronic acids under cobalt catalysis results in addition reactions. This represents a rare example of the cobalt-catalyzed reaction of organoboronic acids. Cobalt shows catalytic activity similar to rhodium, and catalyzes an unprecedented assembly of organoboronic acids and activated alkenes. Copyright
