2239-31-8

Usage

Uses

Used in Pharmaceutical Synthesis:
[1-(aminomethyl)cyclopentyl]methanol is used as a reagent in the preparation of benzimidazole CB2 agonists. These agonists are important in the development of drugs targeting the CB2 receptor, which plays a role in various physiological processes and has potential therapeutic applications in treating inflammatory and neurodegenerative disorders.

InChI:InChI=1/C7H15NO/c8-5-7(6-9)3-1-2-4-7/h9H,1-6,8H2

Upstream product

• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 

Downstream Products

• 204514-22-7 1-(<<(tert-butoxy)carbonyl>amino>methyl)cyclopentane-1-carboxylic acid 
• 457884-62-7 (E)-(8S,11S,17R)-17-(3-Chloro-4-methoxy-benzyl)-8-isobutyl-11-[(S)-1-(3-phenyl-oxiranyl)-ethyl]-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 
• 223763-96-0 (E)-(8S,11S,17R)-17-(3-Chloro-4-methoxy-benzyl)-8-isobutyl-11-((E)-(R)-1-methyl-3-phenyl-allyl)-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 
• 223764-01-0 (E)-(8S,11S,17R)-11-((1R,2R,3S)-3-Chloro-2-hydroxy-1-methyl-3-phenyl-propyl)-17-(3-chloro-4-methoxy-benzyl)-8-isobutyl-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 
• 1328204-90-5 N-((1-(hydroxymethyl)cyclopentyl)methyl)-4-methylbenzenesulfonamide 
• 1568917-15-6 C₂₃H₂₇N₃O₂ 
• 1568916-46-0 C₁₅H₁₄N₂ 

Relevant academic research and scientific papers

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region)

Analogs of the antitumor agents cryptophycins 1 and 8 with dialkyl substitution at C-6 (fragment C) were synthesized and evaluated for in vitro cytotoxicity against human leukemia cells (CCRF-CEM). The activity of these analogs decreased as the size of the substituents at C-6 increased. The C-6 spirocylopropyl compound (2g) was highly potent in vitro and showed excellent antitumor activity in animal models.