204514-22-7

Basic information

• Product Name: Boc-1-aminomethyl-cyclopentane carboxylic acid
• Synonyms: Boc-1-aminomethyl-cyclopentane carboxylic acid;1-(((tert-Butoxycarbonyl)aMino)Methyl)cyclopentanecarboxylic acid;Cyclopentanecarboxylicacid, 1-[[[(1,1-diMethylethoxy)carbonyl]aMino]Methyl]-;1-[(Boc-aMino)Methyl]cyclopentanecarboxylic acid;1-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]cyclopentanecarboxylic acid;1-(((tert-butoxycarbonyl)amino)methyl)cyclopentanecarboxylic acid(WX191664)
• CAS NO: 204514-22-7
• Molecular Formula: C12H21NO4
• Molecular Weight: 243.29944
• Mol File: 204514-22-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 390.2±15.0 °C(Predicted)
• Appearance: /
• Density: 1.129±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.63±0.20(Predicted)
• CAS DataBase Reference: Boc-1-aminomethyl-cyclopentane carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-1-aminomethyl-cyclopentane carboxylic acid(204514-22-7)
• EPA Substance Registry System: Boc-1-aminomethyl-cyclopentane carboxylic acid(204514-22-7)

Safety Data

• Hazardous Substances Data: 204514-22-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 102074-43-1 1-(aminomethyl)cyclopentane carboxylic acid 
• 99092-03-2 methyl 1-(aminomethyl)cyclopentanecarboxylate 
• 40862-12-2 methyl 1-cyanocyclopentanecarboxylate 
• 2239-31-8 3-(1-(aminomethyl)cyclopentyl)methanol 
• 99065-34-6 1-aminomethylcyclopentane-1-carboxylic acid ethyl ester 
• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 
• 223763-91-5 tert-butyl {[1-(hydroxymethyl)cyclopentyl]methyl}carbamate 

Downstream Products

• 223764-01-0 (E)-(8S,11S,17R)-11-((1R,2R,3S)-3-Chloro-2-hydroxy-1-methyl-3-phenyl-propyl)-17-(3-chloro-4-methoxy-benzyl)-8-isobutyl-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 
• 223763-96-0 (E)-(8S,11S,17R)-17-(3-Chloro-4-methoxy-benzyl)-8-isobutyl-11-((E)-(R)-1-methyl-3-phenyl-allyl)-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 
• 457884-62-7 (E)-(8S,11S,17R)-17-(3-Chloro-4-methoxy-benzyl)-8-isobutyl-11-[(S)-1-(3-phenyl-oxiranyl)-ethyl]-7,10-dioxa-16,19-diaza-spiro[4.15]icos-13-ene-6,9,15,18-tetraone 

Relevant articles and documents

TERTIARY AMINE COMPOUND OR IMINE COMPOUND-POLYMER CONJUGATE AND PRODUCTION METHOD THEREFOR

Provided is a compound obtained by conjugating a tertiary amine compound or imine compound, which is useful as a drug, with a polymer, in which a structure D+ having a quaternary ammonium salt or iminium salt formed from a tertiary amine compound or imine compound D and a polymer residue Poly having a carboxy group are bonded to each other via a structure —C(R1)(R2)OC(O)ANHC(═O)—.

Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region)

Analogs of the antitumor agents cryptophycins 1 and 8 with dialkyl substitution at C-6 (fragment C) were synthesized and evaluated for in vitro cytotoxicity against human leukemia cells (CCRF-CEM). The activity of these analogs decreased as the size of the substituents at C-6 increased. The C-6 spirocylopropyl compound (2g) was highly potent in vitro and showed excellent antitumor activity in animal models.