22401-44-1Relevant academic research and scientific papers
How small amounts of impurities are sufficient to catalyze the interconversion of carbonyl compounds and iminium ions, or is there a metathesis through 1,3-oxazetidinium ions? Experiments, speculations, and calculations
Seebach, Dieter,Yoshinari, Tomohiro,Beck, Albert K.,Ebert, Marc-Olivier,Castro-Alvarez, Alejandro,Vilarrasa, Jaume,Reiher, Markus
, p. 1177 - 1203 (2014)
Under the 'best anhydrous' conditions, we were able to achieve, the bicyclic oxazolidinones derived from proline and pivalaldehyde (or cyclohexanone) equilibrate with added carbonyl compounds in (D6)DMSO and in (D6)benzene. With (su
Enantioselective michael addition to α,β-Unsaturated aldehydes: Combinatorial catalyst preparation and screening, reaction optimization and mechanistic studies
Fleischer, Ivana,Pfaltz, Andreas
supporting information; experimental part, p. 95 - 99 (2010/03/26)
Shortcut to chiral catalysts: An efficient combinatorial strategy based on back reaction screening by ESI-MS allows rapid evaluation of organocatalysis for the asymmetric Michael addition to α,β-unsaturated aldehydes (see scheme). An unexpected nonlinear effect has been observed in this reaction, resulting from a double nucleophilic-electrophilic activation mechanism involving two catalyst molecules "Chemical Equation Presented"
