22407-40-5

Basic information

• Product Name: 2-BENZENESULFONYLTHIOPHENE
• Synonyms: 2-(PHENYLSULPHONYL)THIOPHENE;2-(Phenylsulfonyl)thiophene;Phenyl-2-thienylsulfone;2-(BENZENESULFONYL)THIOPHENE 98%;2-BENZENESULFONYLTHIOPHENE
• CAS NO: 22407-40-5
• Molecular Formula: C₁₀H₈O₂S₂
• Molecular Weight: 224.3
• Mol File: 22407-40-5.mol
• Article Data: 19

Chemical Properties

• Melting Point: 123-125°C
• Boiling Point: 391.6 °C at 760 mmHg
• Flash Point: 190.6 °C
• Appearance: /
• Density: 1.34 g/cm³
• Vapor Pressure: 5.5E-06mmHg at 25°C
• Refractive Index: 1.615
• BRN: 146279
• CAS DataBase Reference: 2-BENZENESULFONYLTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZENESULFONYLTHIOPHENE(22407-40-5)
• EPA Substance Registry System: 2-BENZENESULFONYLTHIOPHENE(22407-40-5)

Safety Data

• Hazardous Substances Data: 22407-40-5(Hazardous Substances Data)

Usage

General Description

2-Benzene sulfonylethiophene is a chemical compound that consists of a benzenesulfonyl group attached to a thiophene ring. It is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-BENZENESULFONYLTHIOPHENE has been studied for its potential use in organic electronics and optoelectronics due to its strong electron-accepting properties. It is also used in the production of dyes, pigments, and other specialty chemicals. 2-Benzene sulfonylethiophene is known for its high stability and low toxicity, making it a versatile and valuable chemical in various industrial applications.

InChI:InChI=1/C10H8O2S2/c11-14(12,10-7-4-8-13-10)9-5-2-1-3-6-9/h1-8H

Upstream product

• 52260-00-1 2-thiophene sulfonyl hydrazine 
• 36719-71-8 1-phenyl-3,3-tetramethylenetriazene 
• 98-80-6 phenylboronic acid 
• 3437-95-4 2-Iodothiophene 
• 780-69-8 triethoxyphenylsilane 
• 1003-09-4 2-bromothiophene 
• 591-50-4 iodobenzene 
• 66003-76-7 Diphenyliodonium triflate 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 75241-05-3 thiophene-2-sulfonyl azide 
• 71-43-2 benzene 
• 16629-19-9 thiophene-2-sulfonyl chloride 
• 188290-36-0 thiophene 
• 81745-84-8 2-thienylzinc chloride 

Downstream Products

• 1313758-66-5 4-(5-benzenesulfonylthiophene-2-yl)benzaldehyde 
• 1313758-68-7 methyl 4-(5-benzenesulfonylthiophene-2-yl)benzoate 
• 1313758-67-6 4-(5-benzenesulfonylthiophene-2-yl)benzonitrile 
• 5324-81-2 phenyl 5-methyl-2-thienyl sulfone 
• 128839-71-4 2,3'-bisformylphenyl-2'-thienyl sulfone 
• 98010-06-1 2-phenylsulfonyl-3-thiophenecarboxylic acid 
• 5324-78-7 5-benzenesulfonyl-thiophene-2-carboxylic acid 

Relevant articles and documents

Visible-Light-Mediated Late-Stage Sulfonylation of Boronic Acids via N-S Bond Activation of Sulfonamides

A visible-light-mediated late-stage arylation of N-S bonds in sulfonamides has been developed with using readily available imines as sulfonyl radical source. Diverse complex sulfones could be synthesized by prefunctionalizaiton and subsequent N-S bond ary

Synthesis of Sulfones and Sulfonyl Derivatives using Sodium (tert-butyldimethylsilyl)oxymethanesulfinate

The present invention relates to a method for manufacturing a sulfone and sulfonyl derivative compound using sodium (tert-butyldimethylsilyl)oxymethanesulfinate, which is a novel organic sulfin salt, wherein the novel organic sulfin salt has good stability, environmental friendliness and economy, and is easy to handle, and thus significantly reduces the amount of transition metal catalysts and the amount of organic sulfin salts used when introducing aryl or alkenyl. Also, alkylation, arylation, amination, and fluorination are all possible during secondary functionalization. Therefore, the present invention can be usefully used in preparation and mass production of various kinds of sulfones and derivatives thereof including asymmetric sulfone derivatives.

Hantzsch Ester as a Visible-Light Photoredox Catalyst for Transition-Metal-Free Coupling of Arylhalides and Arylsulfinates

Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (HEH) has been utilized as a visible-light photoredox catalyst for the cross coupling of arylhalides and arylsulfinates without transition metal, sacrificial agent, and mediator. This method is compatible with various functional groups and provides diaryl sulfones in good to high yields. Mechanistic studies indicate that this reaction undergoes the stepwise light irradiation of HE?, single electron transfer (SET) in donor–acceptor complex (DAC) from *HE? to arylhalide, trapping of aryl radical with sulfinate, and SET oxidation of sulfone radical anion by HE. to sulfone by the DAC method.