22416-94-0Relevant articles and documents
Estimation of dissociation constants (pK(a)'s) of oximes from proton chemical shifts in dimethyl sulfoxide solution
Kurtz,D'Silva Th.
, p. 599 - 610 (1987)
In connection with structure-activity studies of insecticidal methyl carbamoyloxime acetylcholinesterase inhibitors, a straightforward approach to estimating pK(a) values of a series of precursor oximes and thiohydroximates has been developed. The pK(a) values of oximes correlate well with the proton chemical shifts of the oximino proton (δ(OH)) in dilute dimethyl sulfoxide-d6 solution. The relationship pK(a) = 29.10 - 1.63δ(OH) was developed from δ(OH) and pK(a) data for 20 compounds available either from the literature or derived experimentally from half-neutralization potentials (ΔHNP). Using this relationship, pK(a) values of more than 200 hydroximino compounds were calculated. The relationship has been extended to also include phenols: pK(a) = 28.15 - 1.55δ(OH) - 3.96I(phenol), where I(phenol) is an indicator variable indicating application of the equation to either a phenol [I(phenol) = 1] or an oxime [I(phenol) = 0].
Compound containing fused heterocyclic structure, preparation method and application of compound and bactericide
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Paragraph 0040-0043, (2020/03/05)
The invention relates to the field of pesticide bactericides, and discloses a compound containing a fused heterocyclic structure, a preparation method and application of the compound and a bactericide. The compound containing the fused heterocyclic structure has a structure as shown in a formula (1) or a formula (2). The compound has the excellent prevention and control effect on plant diseases caused by various oomycete pathogenic bacteria such as phytophthora infestans, phytophthora capsici, pythium ultinum, phytophthora nicotianae, peronophythora litchi and pseudoperonospora cubensis, is obviously superior to a conventional oomycete disease prevention and control agent, namely, dimethomorph, and has a very good market development prospect.
Compound containing naphthenic pyrazole structure and preparation method and application thereof, and bactericide
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Paragraph 0052-0055, (2019/11/21)
The invention relates to the field of pesticide bactericides, and discloses a compound containing a naphthenic pyrazole structure and a preparation method and application thereof, and a bactericide. The compound containing the naphthenic pyrazole structure is a compound as shown in a formula (1) or agrochemically acceptable salts, hydrates and solvates thereof. The compound of the invention has excellent prevention and treatment effect on plant diseases caused by various oomycete pathogens such as Phytophthora infestans, Phytophthora capsici, Pythium ultimum, Phytophthora nicotianae, Peronophthora litchii and cucumber downy mildew, is obviously superior to the conventional oomycete disease control agent dimethomorph, and has a good market development prospect.