2241846-02-4

Basic information

• Product Name: 1,3-dioxoisoindolin-2-yl 2-(3-benzoylphenyl)propanoate
• CAS NO: 2241846-02-4
• Molecular Weight: 399.403
• Mol File: 2241846-02-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-dioxoisoindolin-2-yl 2-(3-benzoylphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dioxoisoindolin-2-yl 2-(3-benzoylphenyl)propanoate(2241846-02-4)
• EPA Substance Registry System: 1,3-dioxoisoindolin-2-yl 2-(3-benzoylphenyl)propanoate(2241846-02-4)

Safety Data

• Hazardous Substances Data: 2241846-02-4(Hazardous Substances Data)

Usage

Structural features

Contains a dioxoisoindolin-2-yl group and a benzoylphenylpropanoate group

Potential applications

Pharmaceutical industry

Biological activities

Unknown, but may have potential due to structural features

Handling precautions

Should be handled with caution and used only by trained professionals in a controlled laboratory setting

Research and development

Further research and development may reveal its potential as a drug candidate for various medical treatments

Chemical class

Complex molecule

Potential as a drug candidate

Yes, due to its structural features and potential biological activities

Safety

Use only in a controlled laboratory setting by trained professionals

Further information

Additional research may be needed to fully understand the properties and potential applications of this compound

Upstream product

• 524-38-9 N-hydroxyphthalimide 
• 22071-15-4 ketoprofen 

Downstream Products

• 67173-18-6 3-(1-hydroxyethyl)benzophenone 

Relevant articles and documents

A donor-acceptor complex enables the synthesis of: E -olefins from alcohols, amines and carboxylic acids

Olefins are prevalent substrates and functionalities. The synthesis of olefins from readily available starting materials such as alcohols, amines and carboxylic acids is of great significance to address the sustainability concerns in organic synthesis. Metallaphotoredox-catalyzed defunctionalizations were reported to achieve such transformations under mild conditions. However, all these valuable strategies require a transition metal catalyst, a ligand or an expensive photocatalyst, with the challenges of controlling the region- and stereoselectivities remaining. Herein, we present a fundamentally distinct strategy enabled by electron donor-acceptor (EDA) complexes, for the selective synthesis of olefins from these simple and easily available starting materials. The conversions took place via photoactivation of the EDA complexes of the activated substrates with alkali salts, followed by hydrogen atom elimination from in situ generated alkyl radicals. This method is operationally simple and straightforward and free of photocatalysts and transition-metals, and shows high regio- and stereoselectivities.

CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS

The invention is directed to methods of converting a carboxylic acid group in a compound, via a redox active ester, to a corresponding boronic ester by treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(ll) salt or a copper salt, and an Mg(ll) salt, in the presence of an alkyllithium or a lithium hydroxide or alkoxide salt. The product pinacolato boronate ester can be cleaved to provide a boronic acid. The invention is also directed to methods of preparing various compounds of medical value comprising boronic acid groups, and to novel boronic-acid containing compounds of medicinal value, including an atorvastatin boronic acid analog, a vancomycin aglycone boronic acid analog, and boronic acid containing elastase inhibitors mCBK319, mCBK320, mCBK323, and RPX-7009.