22421-91-6

Basic information

• Product Name: 2,4-Dimethylphenyl Hydrogen Succinate
• Synonyms: 2,4-Dimethylphenyl Hydrogen Succinate
• CAS NO: 22421-91-6
• Molecular Weight: 222.241
• Mol File: 22421-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-Dimethylphenyl Hydrogen Succinate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethylphenyl Hydrogen Succinate(22421-91-6)
• EPA Substance Registry System: 2,4-Dimethylphenyl Hydrogen Succinate(22421-91-6)

Safety Data

• Hazardous Substances Data: 22421-91-6(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 105-67-9 2,4-Xylenol 

Downstream Products

• 105401-99-8 4-(2-hydroxy-3,5-dimethyl-phenyl)-butyric acid 
• 7356-03-8 4-(2-Hydroxy-3,5-dimethylphenyl)-4-oxobutanoic Acid 

Relevant articles and documents

Photochemical Versus Aluminium Chloride-Catalyzed Fries Rearrangement of Aryl Hydrogen Succinates. Synthesis of 2(3H)-Furanones

The photochemical and aluminium chloride-catalyzed Fries rearrangement of a series of aryl hydrogen succinates 3 a-f to the corresponding 4-oxoacids 1 a-f are compared.Both approaches are complementary: the photochemical process is more general and becomes the method of choice for the succinoylation of phenols supporting alkoxy or hydroxy substituents, while the classical rearrangement is superior in the presence of alkyl or halogen substituents.These results are applied to the preparation of the 2(3H)-furanones 2 a-f. - Keywords: Fries rearrangement; Photo-Fries rearrangement; Aryl hydrogen succinates; 4-Oxoacids; 2(3H)-Furanones.