22422-69-1

Upstream product

• 941-98-0 1'-naphthacetophenone 
• 50-00-0 formaldehyd 
• 660-68-4 diethyl amine hydrochloride 

Downstream Products

• 256382-62-4 (4R,5S)-1,5-Dimethyl-3-((S)-3-methylene-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-2-yl)-4-phenyl-imidazolidin-2-one 
• 637338-42-2 (4S,5R)-1-((2S,3S)-3-Hydroxymethyl-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-2-yl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-66-0 (4S,5R)-1-((2S,5R,6S)-5-Hydroxy-6-naphthalen-1-yl-3-oxo-tetrahydro-pyran-2-yl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-43-3 Acetic acid (2S,3S)-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-3-ylmethyl ester 
• 637338-46-6 (4S,5R)-1-((2S,3R)-3-Hydroxy-3-hydroxymethyl-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-2-yl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-44-4 2,2-Dimethyl-propionic acid (2S,3S)-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-3-ylmethyl ester 
• 637338-57-9 (4S,5R)-1-((2S,3R,5R,6S)-3,5-Dihydroxy-3-hydroxymethyl-6-naphthalen-1-yl-tetrahydro-pyran-2-yl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-47-7 Acetic acid (2S,3S,5R,6S)-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-5-hydroxy-6-naphthalen-1-yl-tetrahydro-pyran-3-ylmethyl ester 
• 637338-45-5 (4S,5R)-1-[(2S,3S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-6-naphthalen-1-yl-3,4-dihydro-2H-pyran-2-yl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-48-8 2,2-Dimethyl-propionic acid (2S,3S,5R,6S)-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-5-hydroxy-6-naphthalen-1-yl-tetrahydro-pyran-3-ylmethyl ester 
• 637338-49-9 Acetic acid (2S,3S,5R,6S)-5-acetoxy-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-6-naphthalen-1-yl-tetrahydro-pyran-3-ylmethyl ester 
• 637338-53-5 (4S,5R)-1-[(2S,3S,5R,6S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-5-hydroxy-6-naphthalen-1-yl-tetrahydro-pyran-2-yl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 637338-50-2 2,2-Dimethyl-propionic acid (2S,3S,5R,6S)-2-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidin-1-yl)-5-(2,2-dimethyl-propionyloxy)-6-naphthalen-1-yl-tetrahydro-pyran-3-ylmethyl ester 
• 904923-02-0 3-benzyloxy-1-naphthalen-1-ylpropan-1-one 

Relevant academic research and scientific papers

Facile catalyst-free synthesis of 2-vinylquinolines via a direct deamination reaction occurring during Mannich synthesis

A facile catalyst-free method for the synthesis of 2-vinylquinolines via a direct deamination reaction during Mannich synthesis has been developed. Instantaneous hydrogen transfer via a six-membered ring intermediate is proposed as a key step for the direct deamination reaction. This reaction strategy tolerates a broad substrate scope and provides a highly efficient way to synthesize 2-vinylquinolines with adequate yields.