22430-63-3

Usage

InChI:InChI=1/C11H12/c1-8-6-10-4-3-5-11(10)7-9(8)2/h3-4,6-7H,5H2,1-2H3

Upstream product

• 32521-03-2 5,6-dimethyl-1-indanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 46037-61-0 1,2-diethynyl-4,5-dimethylbenzene 
• 459457-28-4 ((4,5-dimethyl-1,2-phenylene)bis(ethyne-2,1-diyl))bis(trimethylsilane) 
• 5182-67-2 1,2-diiodo-4,5-dimethyl-benzene 
• 95-47-6 o-xylene 
• 22422-23-7 3-chloro-1-(3,4-dimethyl-phenyl)-propan-1-one 
• 7344-15-2 3,4-dimethyl-cis-bicyclo<4.3.0>nona-3,7-diene 
• 16440-97-4 5,6-Dimethylindan-1-one 

Relevant academic research and scientific papers

TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER

PROBLEM TO BE SOLVED: To provide a transition metal compound catalyst that makes it possible to synthesize an olefin polymer that is soft and has improved catalytic activity and reduced stereoregularity, and a method for producing an olefin polymer. SOLUTION: The present invention provides a compound represented by formula (IV) (X is a σ-binding or π-binding ligand; Y is a Lewis base; Y may be crosslinked to other Y and X; q is an integer of 1-5 and [(valence of M)-2]; r is an integer of 0-3; R1 and R2 independently represent H or halogen, alkyl or the like; R3-R10 are alkyl groups. M is metal elements of groups 3-10 or lanthanoid series in the periodic table; A1-A4 independently represent a crosslinking group composed of group 14 (C, Si, Ge, Sn)). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

CO extrusion in homogeneous gold catalysis: Reactivity of gold acyl species generated through water addition to gold vinylidenes

Herein, we describe a new gold-catalyzed decarbonylative indene synthesis. Synergistic σ,π-activation of diyne substrates leads to gold vinylidene intermediates, which upon addition of water are transformed into gold acyl species, a type of organogold compound hitherto only scarcely reported. The latter are shown to undergo extrusion of CO, an elementary step completely unknown for homogeneous gold catalysis. By tuning the electronic and steric properties of the starting diyne systems, this new reactivity could be exploited for the synthesis of indene derivatives in high yields.

C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF

The present invention provides C-glycoside derivatives and salts thereof, wherein B ring is bonded to A ring via -X- and A ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes related diseases such as an insulin-resistant diseases and obesity.

LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS

A ligand useful to form a metallocene olefin polymerization catalyst comprises:wherein at least R3 and R4 are substituents having at least a bulk of a t-butyl group and, optionally, wherein R1 or R2 may be a bulky substituent group.

Bridged metallocene complex for the (co) polymerization of olefins

A “bridged” bis-cyclopentadienyl complex which can be advantageously used for the formation of a catalytic system active in the (co)polymerization of ethylene and other a-olefins is represented by means of the following formula (II): wherein: M represents a metal selected from titanium, zirconium or hafnium; A′ and A″ each independently represent an anion containing an η5-cyclopentadienyl ring coordinated to M; or R″ each independently represents a group of an anionic nature a-bound to the metal M; B represents an unsaturated bivalent organic residue having from 1 to 30 carbon atoms bound, respectively, to the ring of group and to the -CH2- methylene group by means unsaturated carbon atoms. This complex, combined with a suitable cocata forms a catalyst with a high activity in the poization of olefins, producing polymers with molecular weight, especially in the case of the merization of ethylene with a second α-olefir.

Bridged metallocene complex for the (co)polymerization of olefins

A "bridged" bis-cyclopentadienyl complex which can be advantageously used for the formation of a catalytic system active in the (co)polymerization of ethylene and other α-olefins is represented by means of the following formula (II): wherein: M represents a metal selected from titanium, zirconium or hafnium; A' and A'' each independently represent an anion containing an η5-cyclopentadienyl ring coordinated to M; R' or R'' each independently represents a group of an anionic nature ?-bound to the metal M; B represents an unsaturated bivalent organic residue having from 1 to 30 carbon atoms, bound, respectively, to the ring of group A' and to the -CH2- methylene group by means of unsaturated carbon atoms. This complex, combined with a suitable cocatalyst, forms a catalyst with a high activity in the polymerization of olefins, producing polymers with a high molecular weight, especially in the case of the copolymerization of ethylene with a second α-olefin.

ACYLATION AND CHLORINATION OF 3,4-DIMETHYL-cis-BICYCLONONA-3,7-DIENE

The acylation and chlorination of 3,4-dimethyl-cis-bicyclonona-3,7-diene takes place differently from the reaction with organic acids.During the action of acetic anhydride in the presence of stannic chloride the acetyl group adds at the C4 carbon, and the double bond of the six-membered ring is shifted to the adjacent position.In the reaction of the dichloride of iodobenzene with the diene either monochloro- or dichloro-cis-bicyclonon-7-ene is obtained, depending on the solvent.