224315-51-9

Basic information

• Product Name: 2-Propen-1-ol,3-(2-aminophenyl)-,(2Z)-(9CI)
• Synonyms: 2-Propen-1-ol,3-(2-aminophenyl)-,(2Z)-(9CI)
• CAS NO: 224315-51-9
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 0
• Product Categories: AMINEPRIMARY
• Mol File: 224315-51-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Propen-1-ol,3-(2-aminophenyl)-,(2Z)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-ol,3-(2-aminophenyl)-,(2Z)-(9CI)(224315-51-9)
• EPA Substance Registry System: 2-Propen-1-ol,3-(2-aminophenyl)-,(2Z)-(9CI)(224315-51-9)

Safety Data

• Hazardous Substances Data: 224315-51-9(Hazardous Substances Data)

Upstream product

• 125812-44-4 2-(2-(hydroxymethyl)ethynyl)aniline 
• 224315-42-8 2-[(1Z)-3-hydroxy-1-propenyl]phenylisothiocyanate 
• 19908-02-2 3-Isothiocyanato-cis-zimtaldehyd 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 224315-17-7 Acetic acid (Z)-3-[2-((S)-2-benzyloxycarbonylamino-thiopropionylamino)-phenyl]-allyl ester 
• 224315-30-4 acetic acid 2-[2-(1-benzyloxycarbonylamino-ethyl)-1H-indol-3-yl]-ethyl ester 
• 261951-09-1 Acetic acid (Z)-3-[2-((S)-2-benzyloxycarbonylamino-propionylamino)-phenyl]-allyl ester 
• 224315-09-7 Acetic acid (Z)-3-(2-hexanethioylamino-phenyl)-allyl ester 
• 224315-46-2 (Z)-2-((3-(2-isothiocyanatophenyl)allyl)oxy)tetrahydro-2H-pyran 
• 224315-15-5 Acetic acid (Z)-3-[2-(2-methoxy-thioacetylamino)-phenyl]-allyl ester 
• 224315-07-5 Acetic acid (Z)-3-(2-thioacetylamino-phenyl)-allyl ester 
• 419566-40-8 Acetic acid (Z)-3-{2-[(adamantane-1-carbonyl)-amino]-phenyl}-allyl ester 
• 224315-12-2 2'-[(1Z)-3-(acetyloxy)-1-propenyl](1-adamantane)carbothioanilide 

Relevant articles and documents

Synthesis of 2,3-disubstituted indoles by radical cyclization with hypophosphorous acid and its application to total synthesis of (±)-catharanthine

Radical cyclization of o-alkenylthioanilides using hypophosphorous acid and AIBN in the presence of Et3N proceeded smoothly to furnish the corresponding 2,3-disubstituted indoles in high yields. Utilizing the newly developed cyciization condition, a stereocontrolled total synthesis of (±)-catharanthine has been completed.

Stereocontrolled total synthesis of (±)-catharanthine via radical-mediated indole formation

(matrix presented) A stereocontrolled total synthesis of (±)-catharanthine, 1, has been completed. The key step involves the radical-mediated cyclization of a highly functionalized intermediate to furnish the corresponding indole. The cyclization utilizes