224562-87-2Relevant academic research and scientific papers
Partial synthesis of ciguatoxin (5R)-ABC segment
Saeeng,Isobe
, p. 1911 - 1914 (1999)
An ABC segment of ciguatoxin has been synthesized in a correct enantiomeric form from a D-glucose derivative based on the route for the opposite enantiomer by switching enantiomerism of a pseudosymmetric intermediate. This route, however, has been improved in several steps and ended up with a vinylthioether group for future extension toward the D ring of ciguatoxin molecule.
Synthesis of ciguatoxin (2S,5R)-ABC segment
Saeeng, Rungnapha,Isobe, Minoru
, p. 789 - 798 (2007/10/03)
An (2S,5R)-ABC segment of ciguatoxin has been synthesized based on the previous route for the opposite enantiomer by switching enantiomerism of a pseudosymmetric intermediate. This route has been improved in several steps and ended up with a vinylthioether group for future extension toward the D ring of ciguatoxin molecule.
