224565-94-0Relevant articles and documents
Unusual rearrangements of 2-aroylimidoyl-2-phenylethylidene to 2,5- disubstituted oxazoles
Clark, Adrian D.,Janowski, Wit K.,Prager, Rolf H.
, p. 3637 - 3648 (1999)
Flash vacuum pyrolysis of 2-aroyl-3-phenylisoxazol-5(2H)-ones leads to good yields of 2-aryl-4-phenyloxazoles, and smaller quantities of 2-aryl-5- phenyloxazoles and 5-aryl-2-phenyloxazoles. The mechanism of formation of the 2,5-disubstituted products has been investigated by 13C and substituent labelling, and a non-statistical breakdown of a symmetrical intermediate is invoked to rationalise the product formation.
