224620-23-9Relevant academic research and scientific papers
Catalytic enantioselective conjugate addition of Grignard reagents to cyclic α,β-unsaturated carbonyl compounds
Kanai, Motomu,Nakagawa, Yuichi,Tomioka, Kiyoshi
, p. 3843 - 3854 (1999)
A catalytic asymmetric conjugate addition reaction of organocopper reagents, generated from copper salt, a chiral phosphine, and Grignard reagent, with cyclohexenone is highly dependent on the counter anion of copper species, solvents, Grignard reagents,
Catalytic asymmetric conjugate addition of Grignard reagents mediated by copper(I)-chiral bidentate phosphine complex
Kanai, Motomu,Tomioka, Kiyoshi
, p. 4275 - 4278 (2007/10/02)
A catalytic amount of a chiral phosphine I-copper iodide complex catalyzes the conjugate addition of organomagnesium chlorides to cycloalkenones and pentenolide to give the corresponding addition products in 94-72% ee.
