22494-47-9 Usage
Uses
Used in Pharmaceutical Industry:
Clobuzarit is used as a leukotriene antagonist for the potential treatment of asthma. By inhibiting the action of leukotrienes, it may help to reduce inflammation in the airways and improve asthma symptoms. However, further research is required to establish the safety and effectiveness of clobuzarit for this application and for other potential conditions it may treat.
Check Digit Verification of cas no
The CAS Registry Mumber 22494-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,4,9 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 22494-47:
(7*2)+(6*2)+(5*4)+(4*9)+(3*4)+(2*4)+(1*7)=109
109 % 10 = 9
So 22494-47-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H17ClO3/c1-17(2,16(19)20)21-11-12-3-5-13(6-4-12)14-7-9-15(18)10-8-14/h3-10H,11H2,1-2H3,(H,19,20)
22494-47-9Relevant academic research and scientific papers
Dioxolane derivatives
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, (2008/06/13)
The invention is concerned with novel dioxolane derivatives of the formula: STR1 in which Ra is hydrogen or (1-4C)alkyl and Rb is (1-4C)alkyl or phenyl optionally bearing a halogeno substituent; their production; and their use for the manufacture of certain known anti-arthritic acids of the formula: STR2 and, in particular, those acids in which Ra =Rb =methyl or Ra =ethyl and Rb =phenyl, by a novel reduction process. The preferred reduction procedures involve the use of an alkali metal borohydride or cyanoborohydride in the presence of a noble metal catalyst, or the use of an α-branched alkyl or cycloalkyl Grignard agent. The use of the derivatives of formula I avoids the need for potentially toxic reagents and reactive intermediates in the previously known processes for the production of the acids of formula V.
