224957-10-2

Upstream product

• 105-36-2 ethyl bromoacetate 
• 17334-68-8 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one 

Downstream Products

• 224957-17-9 {4-acetyl-6-oxo-3-phenyl-5-[(5-trifluoromethyl-benzothiazol-2-ylmethyl)-amino]-6H-pyridazin-1-yl}-acetic acid ethyl ester 
• 1026887-49-9 [4-acetyl-5-(4-chloro-benzylamino)-6-oxo-3-phenyl-6H-pyridazin-1-yl]-acetic acid ethyl ester 
• 1026915-24-1 [4-acetyl-5-(4-bromo-phenylamino)-6-oxo-3-phenyl-6H-pyridazin-1-yl]-acetic acid ethyl ester 
• 1027933-61-4 [4-acetyl-5-(4-chloro-phenylamino)-6-oxo-3-phenyl-6H-pyridazin-1-yl]-acetic acid ethyl ester 
• 1026882-60-9 (4-acetyl-5-benzylamino-6-oxo-3-phenyl-6H-pyridazin-1-yl)-acetic acid ethyl ester 
• 1026271-50-0 (4-acetyl-6-oxo-3-phenyl-5-phenylamino-6H-pyridazin-1-yl)-acetic acid ethyl ester 
• 224957-13-5 (4-acetyl-5-nitro-6-oxo-3-phenyl-6H-pyridazin-1-yl)-acetic acid ethyl ester 
• 224956-53-0 (3-methyl-7-oxo-4-phenyl-7H-isoxazolo[3,4-d]pyridazin-6-yl)-acetic acid 

Relevant academic research and scientific papers

Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors

The isoxazolo-[3,4-d]-pyridazin-7-(6H)-one (2) and its corresponding open derivatives 5-acetyl-4-amino-(4-nitro)-6-substituted-3(2H)pyridazinones (3, 4) were used as simplified substrates for the synthesis of new aldose reductase inhibitors with respect t