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1-p-Fluorbenzoyl-2-isopropyliden-hydrazin is a chemical compound with the molecular formula C10H12FN3O. It is a derivative of hydrazine, featuring a p-fluorobenzoyl group attached to the first carbon and an isopropyliden group on the second carbon. 1-p-Fluorbenzoyl-2-isopropyliden-hydrazin is known for its potential applications in pharmaceuticals and agrochemicals, particularly as a building block for the synthesis of various biologically active molecules. Its structure allows for further functionalization and modification, making it a versatile intermediate in organic synthesis. The compound's properties, such as its reactivity and stability, are influenced by the presence of the fluorine atom and the isopropyliden group, which can affect its electronic and steric characteristics.

2252-60-0

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2252-60-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2252-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,5 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2252-60:
(6*2)+(5*2)+(4*5)+(3*2)+(2*6)+(1*0)=60
60 % 10 = 0
So 2252-60-0 is a valid CAS Registry Number.

2252-60-0Relevant academic research and scientific papers

Discovery of a novel series of indolyl hydrazide derivatives as diacylglycerol acyltransferase-1 inhibitors

Kim, Minkyoung,Kwon, Jinsun,Kim, Mun Ock,Singh, Sarbjit,Kim, Sang Kyum,Lee, Kyeong,Lee, Kiho,Lee, Hyun Sun,Choi, Yongseok

supporting information, p. 628 - 635 (2015/05/04)

A novel series of hydrazide derivatives were synthesized as potential diacylglycerol acyltransferase (DGAT) inhibitors. Among them, compounds 8u and 8v exhibited selective and potent DGAT-1 inhibitory activities. In addition, compound 8u dose-dependently inhibited triglyceride synthesis in HepG2 cell lines. Furthermore, treatment with compound 8u for an oral lipid tolerance test showed a significant decrease in plasma triglyceride levels compared with vehicle-treated control animals, indicating delayed absorption of triglyceride after an acute lipid challenge.

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