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N-trifluoroacetyl-L-phenylalanine acid chloride is a chemical compound with the molecular formula C9H8ClF3NO3. It is derived from the amino acid L-phenylalanine, where the amino group is acylated with trifluoroacetic acid to form an amide, and then the carboxylic acid group is converted to an acid chloride. N-trifluoroacetyl-L-phenylalanine acid chloride is a white crystalline solid and is used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and other bioactive compounds. Its structure features a phenyl ring, a trifluoroacetyl group, and an acid chloride functional group, which contribute to its reactivity and utility in chemical transformations.

2252-71-3

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2252-71-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2252-71-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,5 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2252-71:
(6*2)+(5*2)+(4*5)+(3*2)+(2*7)+(1*1)=63
63 % 10 = 3
So 2252-71-3 is a valid CAS Registry Number.

2252-71-3Relevant academic research and scientific papers

Use of N-trifluoroacetyl-protected amino acid chlorides in peptide coupling reactions with virtually complete preservation of stereochemistry

Jass, Paul A.,Rosso, Victor W.,Racha, Saibaba,Soundararajan, Nachimuthu,Venit, John J.,Rusowicz, Andrew,Swaminathan, Shankar,Livshitz, Julia,Delaney, Edward J.

, p. 9019 - 9029 (2007/10/03)

The use of protected amino acid chlorides for peptide coupling reactions has long been avoided due to the extensive racemization that commonly occurs during either the acid chloride formation or the coupling reaction itself. Conditions are described which

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