225220-01-9

Upstream product

• 55277-90-2 Di-S-(2-pyridyl) dithiocarbonate 
• 225219-97-6 (2S,2aS,2bR,5aR,6S)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-hydroxy-2b-methyl-1-oxo-5a-phenylsulfanyl-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 61550-05-8 trimethyl-(5-methyl-furan-2-yloxy)-silane 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 
• 5437-45-6 Benzyl bromoacetate 
• 225219-94-3 (2S,2aS,2bS,5R,5aS,6R)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2b-methyl-1,4-dioxo-5-phenylselanyl-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 225219-96-5 (2S,2aS,2bR,5aR,6S)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2b-methyl-1,4-dioxo-5a-phenylsulfanyl-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 225219-69-2 (2S,2aS,2bS,5aS,6R)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2b-methyl-1,4-dioxo-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 225219-95-4 (2S,2aS,2bS,6R)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2b-methyl-1,4-dioxo-1,2,2a,2b,4,6-hexahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 225219-68-1 <3S-<1R-(tert-butyldimethylsilanyloxy)ethyl>-2S-(2-methyl-5-oxo-2,5-dihydrofuran-2-yl)-4S-oxo-azetidin-1-yl>acetic acid benzyl ester 
• 159332-17-9 3S-<1R-(tert-butyldimethylsilanyloxy)ethyl>-4S-(2S-methyl-5-oxo-2,5-dihydrofuran-2-yl)azetidin-2-one 
• 108-98-5 thiophenol 

Downstream Products

• 225220-02-0 (2S,2aS,2bR,5aR,6S)-2-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methoxy-2b-methyl-1-oxo-5a-phenylsulfanyl-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 
• 225220-03-1 (2S,2aS,2bR,4S,5aR,6S)-5a-Benzenesulfonyl-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methoxy-2b-methyl-1-oxo-octahydro-3-oxa-6a-aza-cyclobuta[a]pentalene-6-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Total synthesis of tricyclic β-lactams

The synthesis of tricyclic carbapenam and penems was achieved by highly stereoselective Lewis acid-catalyzed reactions of 4-substituted 1- trimethylsilyloxyfurans with a 4-acetoxy azetidinone chiron, and further elaboration of the resulting condensation products using intramolecular Michael cyclizations.