22532-46-3

Usage

Type of Compound

Ester

Synthesis

Formed by the reaction of 2-methylphenethyl alcohol with acetic acid

Physical State

Colorless liquid

Aroma

Sweet, floral, fruity; resembles apple, strawberry, and rose

Usage

Synthetic flavor and fragrance ingredient in food and cosmetics; solvent in various applications (e.g., paints, inks, adhesives)

Industry Applications

Food, cosmetic, and paint industries

Upstream product

• 493-05-0 isochromane 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 19819-98-8 2-o-tolylethanol 

Downstream Products

• 1177259-15-2 (-)-(2R,3'S,4'R,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4,4',5,5',6'-hexahydro-1H-spiro[benzo[d]oxepine-2,2'-pyran]-3'-ol 
• 1177259-30-1 (+)-(2S,3'S,4'R,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4,4',5,5',6'-hexahydro-1H-spiro[benzo[d]oxepine-2,2'-pyran]-3'-ol 
• 1177259-06-1 (+)-(2S,3'R,4'S,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4,4',5,5',6'-hexahydro-1H-spiro[benzo[d]oxepine-2,2'-pyran]-3'-ol 
• 1177258-83-1 2-(bromomethyl)phenethyl acetate 
• 1202745-54-7 (-)-2-(2-(((2R,4S)-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-4-(triisopropylsilyloxy)-3,4-dihydro-2H-pyran-6-yl)methyl)phenyl)ethanol 
• 1177258-94-4 (+)-2-(2-(((2R,4R)-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-4-(triisopropylsilyloxy)-3,4-dihydro-2H-pyran-6-yl)methyl)phenyl)ethanol 
• 1177259-24-3 (+)-(2R,3'R,4'S,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4,4',5,5',6'-hexahydro-1H-spiro[benzo[d]oxepine-2,2'-pyran]-3'-ol 

Relevant academic research and scientific papers

Chemoselective acylation of some oxidofunctionalised organolithium compounds

Once oxidofunctionalised organolithium compounds 1 (easily prepared by reductive ring opening of isochroman and phthalan by DTBB-catalysed lithiation) were transmetallated with ZnBr2/CuCN·2LiCl and reacted successively with a carboxylic acid anhydride and an acyl chloride in THF at 0°C, the corresponding differently acylated compounds 4 were obtained after hydrolysis with water. The anhydride performed the O-acylation exclusively and the acyl chloride carried out the C-acylation.

Stereoselective synthesis of benzannulated spiroketals: Influence of the aromatic ring on reactivity and conformation

Image Presented A systematic stereocontrolled synthesis of benzannulated spiroketals has been developed, using kinetic spirocyclization reactions of glycal epoxides, leading to a new AcOH-induced cyclization and valuable insights into the reactivity and c