22536-03-4

Usage

Uses

N-(p-Nitrobenzoyl)glutamic Acid is a derivative of L-Glutamic Acid (G596960), a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory.

Upstream product

• 617-65-2 Glutamic acid 
• 122-04-3 4-nitro-benzoyl chloride 
• 110-94-1 1,5-pentanedioic acid 

Downstream Products

• 4230-33-5 N-(4-aminobenzoyl)-glutamic acid 
• 85646-44-2 N-p-nitrobenzoyl-L-glutamic acid 
• 881740-19-8 N-(4-nitro-benzoyl)-DL-glutamic acid-anhydride 
• 5959-18-2 N-(4-aminobenzoyl)-L-glutamic acid 

Relevant academic research and scientific papers

Synthesis, characterization and biological activity of Cu(II) chelates with some amino acid derivatives

The complexing behaviour of seventeen amino acid derivatives towards Cu(II) has been studied.Complexes of the types Cu(RH)*xH2O, Cu(RH).Cu(OH)2*xH2O and Cu(R'H)2*yH2O have been prepared and characterized by IR, ESR, electronic spectral, magnetic moment and analytical data.On the basis of differences and direction of the shifts in the IR frequencies of vas OCO and vs OCO modes and ESR spectra, bonding modes of carboxylate group have been established.Biological activitu of complexes is more than that of the free metal ion and the ligands.

New glutamic and aspartic derivatives with potent CCK-antagonistic activity

New derivatives of aspartic and glutamic acid were synthesized and evaluated in vitro and in vivo for anti-CCK activity on the guinea pig gallbladder. The anti-CCK activity of some 4-benzamido-glutaramic acid derivatives was a hundred times greater than that of proglutamide, the model compound, and they have been selected for further studies.