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3-bromo-7-fluoroquinoline, a chemical compound with the molecular formula C9H5BrFN, is a substituted quinoline featuring a 3-bromo and 7-fluoro substituent. This versatile building block is widely utilized in pharmaceutical research and drug development due to its unique structure and properties, which influence its reactivity and selectivity in chemical reactions.

225366-90-5

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225366-90-5 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
3-bromo-7-fluoroquinoline serves as a crucial intermediate in the synthesis of various biologically active molecules and pharmaceuticals. Its presence of bromine and fluorine atoms enhances its reactivity and selectivity, making it a valuable component in creating new drugs and agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 225366-90-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,5,3,6 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 225366-90:
(8*2)+(7*2)+(6*5)+(5*3)+(4*6)+(3*6)+(2*9)+(1*0)=135
135 % 10 = 5
So 225366-90-5 is a valid CAS Registry Number.

225366-90-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Bromo-7-fluoroquinoline

1.2 Other means of identification

Product number -
Other names 3-bromo-7-fluoro-quinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:225366-90-5 SDS

225366-90-5Relevant academic research and scientific papers

QUINOLINYL GLUCAGON RECEPTOR MODULATORS

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Page/Page column 41, (2013/03/26)

The present invention provides a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, A1, A2, A3, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.

Effects of oligofluorine substitution on the mutagenicity of quinoline: A study with twelve fluoroquinoline derivatives

Kato, Taka-Aki,Saeki, Ken-Ichi,Kawazoe, Yutaka,Hakura, Atsushi

, p. 149 - 157 (2007/10/03)

A total of 12 variously fluorinated derivatives of quinoline (Q) were tested for their mutagenicity in Salmonella typhimurium TA100 in the presence of S9 mix to investigate the structure-mutagenicity relationship in oligofluorinated quinolines. Nine of th

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