22539-53-3Relevant academic research and scientific papers
A convenient one-pot synthesis of 2-substituted-4,6-diaryl pyrimidines
Sharma,Hussain,Sukhwal,Kothari,Singhal,Verma
, p. 966 - 968 (2007/10/03)
Variously substituted chalcones 1 on treatment with S-benzyl isothiouronium chloride in the presence of ethanol- morpholine/piperidine/pyrrolidine or DMF give 4,6-diaryl-2-(4-morpholinyl/1- piperidinyl/1-pyrrolidinyl) pyrimidines 4a-p and 2-benzyl-thiopyrimidines 3 a-e in a facile one step conversion. An alternate synthesis of 4g, h, j, k is also described.
OXIDATION OF HYDROXYAMINO- AND NITROSOPYRIMIDINES. SYNTHESIS OF 2- AND 4-NITROPYRIMIDINES
Moskalenko, G. G.,Sedova, V. F.,Mamaev, V. P.
, p. 919 - 924 (2007/10/02)
Oxidation of phenyl- and methyl-substituted 2- and 4-hydroxyamino- and -nitrosopyrimidines has given the azoxy- and nitropyrimidines, respectively.The behavior of the nitropyrimidines obtained towards reduction and nucleophilic substitution is considered.
