22550-27-2

Basic information

• Product Name: 1H-Benzimidazole, 1-[(4-nitrophenyl)methyl]-
• CAS NO: 22550-27-2
• Molecular Formula: C14H11N3O2
• Molecular Weight: 253.26
• Mol File: 22550-27-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole, 1-[(4-nitrophenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole, 1-[(4-nitrophenyl)methyl]-(22550-27-2)
• EPA Substance Registry System: 1H-Benzimidazole, 1-[(4-nitrophenyl)methyl]-(22550-27-2)

Safety Data

• Hazardous Substances Data: 22550-27-2(Hazardous Substances Data)

Upstream product

• 706785-08-2 4,5-diethynyl-1-(4-nitro-benzyl)-1H-imidazole 
• 51-17-2 benzoimidazole 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 100-14-1 4-nitrobenzyl chloride 

Downstream Products

• 1313220-20-0 (4-benzoimidazol-1-ylmethyl-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-amine 
• 1313220-19-7 (4-Benzoimidazol-1-ylmethyl-phenyl)-(6-chloro-pyrimidin-4-yl)-amine 
• 41833-21-0 1-(4-hydroxyphenylmethyl)-1H-benzo[d]imidazol 
• 142335-68-0 2-(4-Benzoimidazol-1-ylmethyl-phenoxy)-propionic acid ethyl ester 
• 142335-69-1 N--benzyl>-benzimidazole 
• 51-17-2 benzoimidazole 

Relevant articles and documents

A convenient, efficient and reusable N-heterocyclic carbene-palladium(II) based catalyst supported on magnetite for Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions

In the present work, a new magnetic nanoparticle supported N-heterocyclic carbene-palladium(ii) (NO2-NHC-Pd@Fe3O4) nanomagnetic catalyst was synthesized by a facile multistep synthesis under aerobic conditions using inexpensive chemicals. The NO2-NHC-Pd@Fe3O4 nanomagnetic catalyst was characterized by various analytical techniques such as attenuated total reflectance infrared spectroscopy (ATR-IR), inductively coupled plasma-atomic emission spectroscopy (ICP-AES), energy-dispersive X-ray spectroscopy (EDS), field-emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), X-ray powder diffraction (XRD), thermogravimetric analysis (TGA) and Brunauer-Emmett-Teller surface area analysis (BET). The synthesized NO2-NHC-Pd@Fe3O4 nanomagnetic catalyst showed excellent catalytic activity in both Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions for various substrates under mild reaction conditions. Recovery of the NO2-NHC-Pd@Fe3O4 nanomagnetic catalyst from the reaction mixture was easily accomplished by applying an external magnet. The recovered NO2-NHC-Pd@Fe3O4 nanomagnetic catalyst exhibited very good catalytic activity up to seven recycles in Suzuki-Miyaura and five recycles in Mizoroki-Heck cross-coupling reactions without considerable loss of its catalytic activity.

Bergman cycloaromatization of imidazole-fused enediynes: The remarkable effect of N-aryl substitution

A series of N-aryl substituted 'imidazole-fused' (Z) 3-ene-1,5-diynes was prepared and kinetic parameters for their Bergman cycloaromatization reactivities were determined. N-Arylation enhanced rates relative to N-alkyl derivatives by up to sevenfold (ANOVA p0.0001). The greatest enhancement was exhibited by the N-phenyl derivative (sevenfold at 145°C).

Structure-activity studies on a 1,2,3-triazole derivative, a potent in vitro inhibitor of prostaglandin synthesis: The role of the heterocyclic ring

This paper reports further structural modifications concerning the 1,2,3- triazole ring of the compound A, an effective in vitro inhibitor of prostaglandin synthesis. The introduction of different heterocyclic rings provided further information about of t