225640-48-2

Basic information

• Product Name: benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate
• Synonyms: benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate
• CAS NO: 225640-48-2
• Molecular Weight: 628.861
• Mol File: 225640-48-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate(225640-48-2)
• EPA Substance Registry System: benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate(225640-48-2)

Safety Data

• Hazardous Substances Data: 225640-48-2(Hazardous Substances Data)

Upstream product

• 225640-43-7 tert-butyl (phenyl 2-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranosid)uronate 
• 225640-44-8 methyl (phenyl 2-O-benzyl-1-thio-β-D-galactopyranosid)uronate 
• 124476-97-7 phenyl 2-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside 
• 100-39-0 benzyl bromide 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 225640-46-0 benzyl (phenyl 2,3-di-O-benzyl-1-thio-β-D-galactopyranosid)uronate 

Relevant articles and documents

Synthesis of the two monomethyl esters of the disaccharide 4-O-α-D-galacturonosyl-D-galacturonic acid and of precursors for the preparation of higher oligomers methyl uronated in definite sequences

Methyl (α-D-galactopyranosyluronic acid)-(1→4)-D-galactopyranuronate and methyl α-D-galactopyranosyluronate-(1→4)-D-galactopyranuronic acid have been synthesized by coupling methyl (benzyl 2,3-di-O-benzyl-β-D-galactopyranosid)uronate (3) or benzyl (benzyl 2,3-di-O-benzyl-β-D-galactopyranosid)uronate (4) with benzyl (phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranosid)uronate and methyl (phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranosid)uronate, respectively, using N-iodosuccinimide and trifluoromethanesulphonic acid as promoters, followed by removal of the benzyl groups. The 4'-OH unprotected dimers benzyl (methyl 2,3-di-O-benzyl-α-D-galactopyranosyluronate)-(1→4)-(benzyl 2,3-di-O-benzyl-β-D-galactopyranosid)uronate and methyl (benzyl 2,3-di-O-benzyl-α-D-galactopyranosyluronate)-(1→4)-(benzyl 2,3-di-O-benzyl-β-D-galactopyranosid)uronate were prepared from methyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate and benzyl (phenyl 2,3-di-O-benzyl-1-thio-4-O-trimethylsilyl-β-D-galactopyranosid)uronate and acceptors 4 or 3, respectively. These compounds have been designed to serve as precursors for the preparation of higher-membered d-galacturonic acid oligomers methyl esterified in definite positions. Copyright (C) 1998 Elsevier Science Ltd.