225642-66-0

Upstream product

• 225642-87-5 (Z)-(3S,4S)-1-(tert-Butyl-diphenyl-silanyloxy)-4-chloro-9-[1,3]dithian-2-yl-non-6-en-3-ol 
• 225642-89-7 (Z)-(7S,8S)-10-(tert-Butyl-diphenyl-silanyloxy)-7-chloro-8-hydroxy-dec-4-enoic acid 
• 225642-70-6 tert-Butyl-[2-((5Z,8Z)-(2S,3S)-3-chloro-9-ethyl-2,3,4,7-tetrahydro-oxonin-2-yl)-ethoxy]-diphenyl-silane 
• 225642-73-9 9-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-8-chloro-4,7,8,9-tetrahydro-3H-oxonin-2-one 
• 225642-75-1 (3R,4R)-1-(tert-Butyl-dimethyl-silanyloxy)-3-chloro-9-[1,3]dioxolan-2-yl-non-6-yn-4-ol 
• 225642-77-3 (Z)-(3R,4R)-1-(tert-Butyl-dimethyl-silanyloxy)-3-chloro-9-[1,3]dioxolan-2-yl-non-6-en-4-ol 
• 225642-81-9 tert-Butyl-{2-[(2S,3R)-3-((Z)-5-[1,3]dioxolan-2-yl-pent-2-enyl)-oxiranyl]-ethoxy}-dimethyl-silane 
• 225642-85-3 (Z)-(3S,4S)-4-Chloro-9-[1,3]dithian-2-yl-non-6-ene-1,3-diol 
• 225642-82-0 2-[(2S,3R)-3-((Z)-5-[1,3]Dioxolan-2-yl-pent-2-enyl)-oxiranyl]-ethanol 
• 71948-69-1 2-(but-3-yn-1-yl)-1,3-dioxolane 
• 558459-43-1 (2S,3R,8R,9S)-8-benzyloxy-2-[2-(tert-butyl-diphenyl-silanyloxy)ethyl]-9-ethyl-2,3,4,7,8,9-hexahydro-oxonin-3-ol 
• 558459-46-4 1-[(2S,3R,8R,9S)-3-(tert-butyldimethyl-silanyloxy)-9-ethyl-8-benzyloxy-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-3-methylbutane-2,3-diol 
• 558459-39-5 {(1R)-1-[(1S)-1-((1S,2R)-2-benzyloxy-1-ethyl-pent-4-enyloxy)-2-(3,3-dimethyloxiranyl)-ethyl]-but-3-enyloxy}-tert-butyl-dimethyl-silane 
• 558459-25-9 [(1R,2S)-1-allyl-2-((1S,2R)-2-benzyloxy-1-ethyl-pent-4-enyloxy)-5-methyl-hex-4-enyloxy]-tert-butyl-dimethyl-silane 

Downstream Products

• 71939-43-0 (+)-obtusenyne 
• 225642-64-8 [(2S,3S,8S,9S)-2-(8-bromo-3-chloro-9-ethyl-2,3,4,7,8,9-hexahydro-oxonin-2-yl)-ethoxy]-tert-butyl-diphenyl-silane 

Relevant academic research and scientific papers

Enantioselective total synthesis of (+)-obtusenyne

A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-clos

Determination of the absolute configurations of norte's obtusenynes by total syntheses of (12R,13R)-(-)- and (12S,13R)-(+)-obtusenynes

The total syntheses of (12R,13R)-(-)-obtusenynes and (12S,13R)-(+)-obtusenynes were achieved. The absolute configurations of the obtusenynes isolated by Norte from Laurencia pinnatifida were clarified as the former.