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2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE, also known as 4-(Chloromethyl)-3-nitrobenzotrifluoride, is a chlorinated aromatic compound characterized by the molecular formula C8H6ClF3NO2. It features a trifluoromethyl group and a nitro group attached to a benzene ring, making it a reactive and potentially hazardous chemical that necessitates careful handling and storage. 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE serves as a crucial intermediate in the synthesis of various products, including pharmaceuticals, agrochemicals, dyes, and pigments.

225656-59-7

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225656-59-7 Usage

Uses

Used in Pharmaceutical Industry:
2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of new drug molecules with specific therapeutic properties, contributing to the advancement of medicine and healthcare.
Used in Agrochemical Industry:
In the agrochemical sector, 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE is utilized as a precursor in the synthesis of agrochemicals. Its reactive nature enables the production of compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals, helping to improve crop protection and yield.
Used in Dye and Pigment Production:
2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE is employed as a key intermediate in the manufacturing process of dyes and pigments. Its chemical properties facilitate the synthesis of a wide range of colorants used in various industries, such as textiles, plastics, and printing inks, enhancing the colorfastness and vibrancy of the final products.
Used in Chemical Research:
2-NITRO-4-(TRIFLUOROMETHYL)BENZYL CHLORIDE also serves as a valuable compound in chemical research and development. Its unique structure and reactivity make it an interesting subject for studies aimed at understanding reaction mechanisms, exploring new synthetic routes, and discovering novel applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 225656-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,5,6,5 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 225656-59:
(8*2)+(7*2)+(6*5)+(5*6)+(4*5)+(3*6)+(2*5)+(1*9)=147
147 % 10 = 7
So 225656-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClF3NO2/c9-4-5-1-2-6(8(10,11)12)3-7(5)13(14)15/h1-3H,4H2

225656-59-7 Well-known Company Product Price

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  • Alfa Aesar

  • (H32191)  2-Nitro-4-(trifluoromethyl)benzyl chloride, 98%   

  • 225656-59-7

  • 1g

  • 509.0CNY

  • Detail
  • Alfa Aesar

  • (H32191)  2-Nitro-4-(trifluoromethyl)benzyl chloride, 98%   

  • 225656-59-7

  • 10g

  • 3176.0CNY

  • Detail

225656-59-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Nitro-4-(trifluoromethyl)benzyl chloride

1.2 Other means of identification

Product number -
Other names 1-(chloromethyl)-2-nitro-4-(trifluoromethyl)benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:225656-59-7 SDS

225656-59-7Relevant academic research and scientific papers

Vicarious Nucleophilic Chloromethylation of Nitroaromatics

Khutorianskyi, Viktor V.,Klepetá?ová, Blanka,Beier

supporting information, p. 5443 - 5446 (2019/07/03)

Nitroaromatics substituted with electron-acceptor or electron-donor groups undergo vicarious nucleophilic substitution with the lithium salt of dichloromethane to provide chloromethyl-substituted nitroaromatics in good to high yields. The methodology represents a new strategy for the synthesis of benzyl chlorides.

Enantioselective synthesis of diarylcyclopropanecarboaldehydes by organocatalysis

Chen, Xuyun,Yu, Yang,Liao, Ziyang,Li, Hao,Wang, Wei

supporting information, p. 5742 - 5745 (2016/12/03)

An efficient synthetic method for chiral trisubstituted diarylcyclopropanecarboaldehydes has been developed from substituted benzyl chloride and α,β-unsaturated aldehydes. The reactions were catalyzed by chiral amine catalyst under mild condition to afford the chiral diarylcyclopropanecarboaldehydes in good to high yields and up to excellent enantioselectivities.

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