22568-06-5

Basic information

• Product Name: Benzenamine, N,N-dimethyl-4-[(1E)-2-nitroethenyl]-
• Synonyms: Benzenamine, N,N-dimethyl-4-[(1E)-2-nitroethenyl]-;(E)-N,N-dimethyl-4-(2-nitrovinyl)aniline
• CAS NO: 22568-06-5
• Molecular Formula: C₁₀H₁₂N₂O₂
• Molecular Weight: 192.21448
• Mol File: 22568-06-5.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenamine, N,N-dimethyl-4-[(1E)-2-nitroethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N,N-dimethyl-4-[(1E)-2-nitroethenyl]-(22568-06-5)
• EPA Substance Registry System: Benzenamine, N,N-dimethyl-4-[(1E)-2-nitroethenyl]-(22568-06-5)

Safety Data

• Hazardous Substances Data: 22568-06-5(Hazardous Substances Data)

Upstream product

• 625-75-2 nitroacetic acid 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 75-52-5 nitromethane 

Downstream Products

• 128640-21-1 [1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid ethyl ester 
• 128640-21-1 (R)-[(R)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid ethyl ester 
• 128640-21-1 (R)-[(S)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid ethyl ester 
• 128640-23-3 (R)-[(R)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid isopropyl ester 
• 128640-23-3 (R)-[(S)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid isopropyl ester 
• 128640-22-2 (R)-[(R)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid propyl ester 
• 128640-22-2 (R)-[(S)-1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-phenyl-phosphinic acid propyl ester 
• 75-52-5 nitromethane 
• 23630-92-4 1,1-dimethylamino-4-(2-nitroethyl)benzene 
• 116545-09-6 4-N,N-dimethylamino-ω-nitroacetophenone 
• 1004794-73-3 diethyl (R,R)-2-(4-(dimethylamino)phenyl)-3-nitro-1-phenylpropylphosphonate 
• 102880-23-9 4-dimethylamino-phenethylamine; dihydrochloride 

Relevant articles and documents

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PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME

The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX) / histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.

One-Step, Effective, and Cascade Syntheses of Highly Functionalized Cyclopentenes with High Diastereoselectivity

Tetrabutylammonium fluoride works as an effective organocatalyst for the cycloaddition between phenacylmalononitriles and electron-deficient olefins (having substituent groups of NO2, CHO, and COR), providing a facile synthetic route to versatile multifunctionalized cyclopentenes having an allylic quaternary carbon center bearing both cyano and carboxamide groups with high yields and high diastereoselectivity. Preliminary studies reveal that these functionalized cyclopentenes are convenient precursors for making α-cyano-functionalized cyclopentadienone oximes.