22590-92-7 Usage
General Description
4-(Hydrazinocarbonyl)benzamide is a chemical compound with the molecular formula C8H9N3O2. It is a white to off-white solid that is soluble in organic solvents. This chemical is used in pharmaceutical research as it exhibits anti-inflammatory and analgesic properties. It is also being studied for its potential use in the treatment of various diseases, including cancer and neurological disorders. Additionally, 4-(Hydrazinocarbonyl)benzamide has shown promise as a potential precursor for the synthesis of other bioactive compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 22590-92-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,9 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22590-92:
(7*2)+(6*2)+(5*5)+(4*9)+(3*0)+(2*9)+(1*2)=107
107 % 10 = 7
So 22590-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H9N3O2/c9-7(12)5-1-3-6(4-2-5)8(13)11-10/h1-4H,10H2,(H2,9,12)(H,11,13)
22590-92-7Relevant articles and documents
Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists
Lin, Hua,Doebelin, Christelle,Patouret, Rémi,Garcia-Ordonez, Ruben D.,Ra Chang, Mi,Dharmarajan, Venkatasubramanian,Bayona, Claudia Ruiz,Cameron, Michael D.,Griffin, Patrick R.,Kamenecka, Theodore M.
, p. 1313 - 1319 (2018/03/21)
Herein we report the design and synthesis of a series of simple phenol amide ERRγ agonists based on a hydrazone lead molecule. Our structure activity relationship studies in this series revealed the phenol portion of the molecule to be required for activity. Attempts to replace the hydrazone with more suitable chemotypes led to a simple amide as a viable alternative. Differential hydrogen-deuterium exchange experiments were used to help understand the structural basis for binding to ERRγ and aid in the development of more potent ligands.
