22613-33-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Cyclohexen-1-amine, hydrochloride is used as an intermediate for the synthesis of various pharmaceutical compounds. Its amine functional group allows for the formation of C-C and C-N bonds, which are essential in the creation of complex drug molecules.
Used in Chemical Industry:
2-Cyclohexen-1-amine, hydrochloride is used as a reagent in organic chemistry reactions, particularly in the formation of C-C and C-N bonds. Its stability and ease of handling make it a preferred choice for various organic synthesis processes.
Used in Pesticide Production:
2-Cyclohexen-1-amine, hydrochloride is used in the production of pesticides, where its chemical properties contribute to the development of effective and stable formulations.
Used in Dye Production:
2-Cyclohexen-1-amine, hydrochloride is used in the production of dyes, where its chemical structure allows for the creation of a wide range of colors and properties.
Used in Fine Chemicals Production:
2-Cyclohexen-1-amine, hydrochloride is used in the production of other fine chemicals, where its versatility and reactivity contribute to the development of high-quality specialty products.

Upstream product

• 76644-52-5 rac-3-acetoxycyclohexene 
• 57981-18-7 N-cyclohex-2-enyl-4-methyl-benzenesulfonamide 
• 16717-84-3 3-azido-1-cyclohexene 
• 1521-51-3 rac-3-bromocyclohexene 
• 110-83-8 cyclohexene 
• 106348-43-0 (1S)-(-)-N-(cyclohex-2-en-1-yl)hydroxylamine 

Downstream Products

• 10514-92-8 trans-2-amino-1-cyclohexanethiol 
• 10514-92-8 cis-2-amino-cyclohexanethiol 
• 91230-17-0 benzyl (RS)-cyclohex-2-en-1-ylcarbamate 
• 91230-16-9 3-(N-tert-butoxycarbonylamino)cyclohexene 
• 4981-52-6 N-(cyclohex-2-en-1-yl)pivalamide 
• 4654-36-8 (RS)-N-(cyclohex-2-en-1-yl)benzamide 
• 175222-95-4 N-(cyclohex-2-en-1-yl)-4-nitrobenzenesulfonamide 
• 62854-15-3 3-benzamido-cis-1,2-epoxycyclohexane 
• 39819-72-2 N-Cyclohex-2-enyl-acetamide 
• 10514-97-3 (+/-)-cis-1-benzoylamino-2-benzoylmercapto-cyclohexane 
• 10514-97-3 (+/-)-trans-1-benzoylamino-2-benzoylmercapto-cyclohexane 
• 69509-88-2 (+/-)-N-(trans-2-mercapto-cyclohexyl)-benzamide 
• 10514-96-2 optically inactive bis-(cis-2-benzoylamino-cyclohexyl)-disulfide 

Relevant academic research and scientific papers

One-Pot Synthesis of Primary and Secondary Aliphatic Amines via Mild and Selective sp3 C?H Imination

The direct replacement of sp3 C?H bonds with simple amine units (?NH2) remains synthetically challenging, although primary aliphatic amines are ubiquitous in medicinal chemistry and natural product synthesis. We report a mild and selective protocol for preparing primary and secondary aliphatic amines in a single pot, based on intermolecular sp3 C?H imination. The first C?H imination of diverse alkanes, this method shows useful site-selectivity within substrates bearing multiple sp3 C?H bonds. Furthermore, this reaction tolerates polar functional groups relevant for complex molecule synthesis, highlighted in the synthesis of amine pharmaceuticals and amination of natural products. We characterize a unique C?H imination mechanism based on radical rebound to an iminyl radical, supported by kinetic isotope effects, stereoablation, resubmission, and computational modeling. This work constitutes a selective method for complex amine synthesis and a new mechanistic platform for C?H amination.

Synthesis of sultams by intramolecular Heck reaction

A novel access to α-methylene-γ-sultams via the intramolecular Heck reaction of α-bromovinylsulfonamides derived from allylic amines is reported. These heterocycles are potent Michael acceptors towards sulfur nucleophiles.

Asymmetric synthesis of primary amines from alkenes and chiral chloronitroso sugar derivatives

A variety of alkenes 5 - 15, 38, 39 react with chloronitroso sugar derivatives 1 - 3 regioselectively at ambient temperature to give chiral hydroxylamines in 60-80% yield. In addition to these products of a formal ene reaction joined by a subsequent hydro

An Efficient Route to Both Enantiomers of N-(p-Tolylsulfonyl)-benzenesulfonimidamide and Their Use for Asymmetric Allylic Amination of Olefins

The chiral compounds (R)- and (S)-N-(p-tolylsulfonyl)benzenesulfonimidamide have been prepared effiently from N-(p-tolylsulfonyl)benzenesulfonimidoyl chloride and both enenatiomers were transformed into chiral selenium diimide reagents, (S)- and (R)-N,N'-

PALLADIUM(0) CATALYZED AZIDATION AND AMINATION OF ALLYL ACETATES. SELECTIVE SYNTHESIS OF ALLYL AZIDES AND PRIMARY ALLYLAMINES

Palladium catalyzed reaction of allyl acetates with azide ion gives allyl azides, which are readily converted into the corresponding primary allylamines upon treatment with PPh3/NaOH.