226247-61-6Relevant articles and documents
Regioselective functionalization of purine derivatives at positions 8 and 6 using hindered TMP-amide bases of Zn and Mg
Crestey, Fran?ois,Zimdars, Silvia,Knochel, Paul
, p. 3029 - 3037 (2013/11/06)
A broad range of purine derivatives were efficiently metalated at positions 8 and 6 using TMP-amide bases. This provided polysubstituted purines in good to very good yields after subsequent trapping of the zinc or magnesium intermediates with various elec