22632-10-6 Usage
General Description
4-Pyrimidinamine, N-methyl- (9CI) is a chemical compound with the molecular formula C5H6N4. It is also known as N-methyl-4-aminopyrimidine and is a member of the pyrimidine family of compounds. This chemical is used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It has applications in the production of antiviral drugs, herbicides, and other products. 4-Pyrimidinamine, N-methyl- (9CI) is a white crystalline solid with a melting point of 110-112°C and a boiling point of 264-265°C. It is an important intermediate in organic synthesis and has various industrial uses.
Check Digit Verification of cas no
The CAS Registry Mumber 22632-10-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,6,3 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22632-10:
(7*2)+(6*2)+(5*6)+(4*3)+(3*2)+(2*1)+(1*0)=76
76 % 10 = 6
So 22632-10-6 is a valid CAS Registry Number.
22632-10-6Relevant articles and documents
Efficient ruthenium-catalyzed N-methylation of amines using methanol
Dang, Tuan Thanh,Ramalingam, Balamurugan,Seayad, Abdul Majeed
, p. 4082 - 4088 (2015/11/11)
An in situ-generated complex from [RuCpCl2]2 and dpePhos ligand is reported as an efficient catalyst in the presence of 5 mol % of LiOtBu for the N-methylation of amines using methanol as the methylating agent at moderate conditions, following hydrogen borrowing strategy. This simple catalyst system provides selective N-monomethylation of substituted primary anilines and sulfonamides as well as N,N dimethylation of primary aliphatic amines in excellent yields at 40-100 °C with good tolerance to reducible functional groups. The catalytic intermediate CpRu(dpePhos)H was isolated and was shown to be active for methylation in the absence of base.
