2264-12-2

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 20 carbon (C) atoms, 13 hydrogen (H) atoms, 2 fluorine (F) atoms, and 3 nitrogen (N) atoms.

Explanation

The compound is derived from the benzimidazole core structure, which is a fused ring system containing both benzene and imidazole rings. It has two fluorophenyl groups attached to it, which are phenyl rings with a fluorine atom in the 4-position.

Explanation

Benzimidazole derivatives are known for their various biological activities, making them valuable in the development of new drugs and therapies.

Explanation

The compound may exhibit these properties due to its benzimidazole core structure and the presence of fluorophenyl groups, which can influence its interactions with biological targets.

Explanation

The fluorine atoms in the 4-position of the phenyl groups can contribute to the compound's pharmacological properties and bioavailability, as fluorine is known to modulate the properties of organic compounds.

Explanation

While the compound has potential applications in medicinal chemistry and pharmaceutical research, more studies are required to determine its specific uses and effectiveness in various biological and pharmaceutical applications.

Structure

Benzimidazole derivative with two fluorophenyl groups

Potential Applications

Medicinal chemistry and pharmaceutical research

Biological Activities

Anti-cancer, anti-inflammatory, and anti-microbial properties

Presence of Fluorine Atoms

In the 4-position of the phenyl group

Further Research

Needed to fully understand potential uses

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 459-46-1 4-Fluorobenzyl bromide 
• 7191-70-0 N-(4''-fluorobenzyl)-1,2-phenylenediamine 
• 459-56-3 4-fluorobenzylic alcohol 
• 88-74-4 2-nitro-aniline 
• 1493-27-2 ortho-nitrofluorobenzene 
• 134227-41-1 1-(4-fluorophenyl)-N-[(4-fluorophenyl)methyl]methanamine 

Downstream Products

• 1239692-18-2 Ir(1-(4-fluorobenzyl)-2-(4-fluorophenyl)-1-H-benzo[d]imidazole)((3-pyridin-2-yl)4,5,6,7-tetrahydro-2H-indazole) 
• 1239692-19-3 [iridium(III)chloride(1-(4-fluorobenzyl)-2-(4-fluorophenyl)-1H-benzo[d]imidazole)2]2 

Relevant academic research and scientific papers

Computational studies of 1,2-disubstituted benzimidazole derivatives

Some 1,2-disubstituted benzimidazole derivatives (1-6) have been synthesized and characterized by mass, 1H, 13C NMR and elemental analysis. XRD analysis was carried out for 1-(4-methylbenzyl)-2-p- tolyl-1H-benzo[d]imidazole. Calculat

l-Proline catalyzed selective synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles

l-Proline (10 mol %) was found to be a versatile organocatalyst for the selective synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles from a wide range of substituted o-phenylenediamines and aldehydes in moderate to excellent isolated yields (32-95%) under

Synthesis, spectral studies and solvatochromism of some novel benzimidazole derivatives-ESIPT process

Some novel benzimidazole derivatives were synthesized and characterized by 1H, 13C NMR mass and elemental analysis. XRD analysis was carried out for 1-(4-methylbenzyl)-2-p-tolyl-1H-benzo[d]imidazole. The solvent effect on the absorpt

Selective quenching of benzimidazole derivatives by Cu2+ metal ion

It is a very big challenge to develop a Cu2+ selective fluorescent sensor with the ability to exclude the interference of some metal ions such as Fe3+, Mg2+, Ag+, K+ and Na+. Herein, we rep

A facile and highly chemoselective synthesis of 1,2-disubstituted benzimidazoles using hierarchical nanoporous material

A highly ordered nanoporous aluminosilicate (MMZY) is prepared and employed as a catalyst for the synthesis of benzimidazoles from 1,2-diaminobenzene and aromatic aldehydes. In all the cases, the reactions are highly chemoselective and afford 1,2-disubstituted benzimidazoles in excellent yield. The catalyst was characterized by electron microscopy and X-ray methods and its other advantages like functional tolerance, mildness of the reaction conditions, easy separation, and reusability are also highlighted.

Lifetime time measurements, Kamlet-Taft and Catalan solvatochromism of some 2-aryl benzimidazole derivatives

Some 2-aryl benzimidazole derivatives (1-6) have been prepared and characterized by different spectral techniques. Fluorescence lifetime of synthesized 2-aryl benzimidazole derivatives was calculated. Kamlet-Taft and Catalan solvatochromism of synthesized

Effective fluorescent chemosensors for the detection of Zn2+ metal ion

Benzimidazole derivatives synthesized from three components assembling condensation reaction behaves as a selective fluorescent sensor for Zn 2+ metal ion. These benzimidazole derivatives were characterized by 1H, 13C NMR,

Bismuth(III)-catalyzed rapid and highly efficient synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles in water

2-Aryl-1-arylmethyl-1H-benzimidazoles are prepared in high yields under extremely mild conditions via the condensation of aryl-1,2-diamines with aromatic aldehydes using 10 m.ol% of bismuth triflate in water. The use of water and readily available bismuth

An efficient facile and one-pot synthesis of benzodiazepines and chemoselective 1,2-disubstituted benzimidazoles using a magnetically retrievable Fe3O4 nanocatalyst under solvent free conditions

Benzodiazepine and chemoselective 1,2-disubstituted benzimidazole derivatives were synthesized by the condensation reaction of o-phenylenediamine with ketones and aryl aldehydes using Fe3O4 nanoparticles as a recyclable catalyst unde

Docking investigation and binding interaction of benzimidazole derivative with bovine serum albumin

1H NMR, 13C NMR and Mass spectral analysis have been made for 1-(4-fluorobenzyl)-2-(4-fluorophenyl)-1H-benzo[d]imidazole (FBFPB). The mutual interaction of FBFPB with bovine serum albumin (BSA) was investigated using absorption, fluo