226545-68-2

Upstream product

• 25024-53-7 Boc-His(Dnp)-OH 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 2130-96-3 O-benzyl-N-tert-butoxycarbonyl-L-tyrosine 
• 52142-01-5 H-Tyr(Bzl)-OBzl_.HCl 
• 100-51-6 benzyl alcohol 
• 226545-66-0 N^α-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosine benzyl ester 
• 92515-43-0 (S)-3-(4-benzyloxyphenyl)-2-(tert-butoxycarbonylamino)propionic acid benzyl ester 

Downstream Products

• 226545-74-0 N^α-tert-butoxycarbonyl-L-prolyl-L-isoleucyl-glycyl-N^im-2,4-dinitrophenyl-L-histidyl-L-leucyl-O-benzyl-L-tyrosine benzyl ester 
• 226545-72-8 N^α-tert-butoxycarbonyl-L-isoleucyl-glycyl-N^im-2,4-dinitrophenyl-L-histidyl-L-leucyl-O-benzyl-L-tyrosine benzyl ester 
• 775564-76-6 L-isoleucyl-glycyl-N^im-2,4-dinitrophenyl-L-histidyl-L-leucyl-O-benzyl-L-tyrosine benzyl ester hydrochloride 
• 226545-70-6 N^α-tert-butoxycarbonylglycyl-N^im-2,4-dinitrophenyl-L-histidyl-L-leucyl-O-benzyl-L-tyrosine benzyl ester 

Relevant academic research and scientific papers

Synthesis of cancer peptide antigen-lipid A analog conjugates for synthetic vaccines

Conjugates 6 and 7 of cancer peptide antigen with N-tetradecanoyl L- serine-β-alanine-containing D-glucosamine derivative structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers. The mitogenic activities of compounds 6 and 7 were stronger than that of lipid A analog 3.