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Cyclohex-1-en-4-yl fluoride, also known as 4-fluorocyclohexene, is an organic compound with the chemical formula C6H9F. It is a colorless liquid that is insoluble in water but soluble in organic solvents. cyclohex-1-en-4-yl fluoride is a derivative of cyclohexene, where one hydrogen atom on the cyclohexane ring is replaced by a fluorine atom. Cyclohex-1-en-4-yl fluoride is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of fluoxetine, a widely prescribed antidepressant. It is also employed in the preparation of other fluorinated organic compounds. Due to its reactivity and potential applications, cyclohex-1-en-4-yl fluoride is a significant compound in the field of organic chemistry and fluorine chemistry.

2266-53-7

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2266-53-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2266-53-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,6 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2266-53:
(6*2)+(5*2)+(4*6)+(3*6)+(2*5)+(1*3)=77
77 % 10 = 7
So 2266-53-7 is a valid CAS Registry Number.

2266-53-7Downstream Products

2266-53-7Relevant academic research and scientific papers

Accelerating influence of the gem-difluoromethylene group in a ring-closing olefin metathesis reaction. A Thorpe-Ingold effect?

Urbina-Blanco, Cesar A.,Skibinski, Maciej,O'Hagan, David,Nolan, Steven P.

supporting information, p. 7201 - 7203 (2013/08/15)

The gem-difluoromethylene (CF2) group significantly accelerates ring-closing metathesis of 1,8-nonadienes relative to the methylene (CH 2) group demonstrating similar rate accelerations to that observed for the classic Thorpe-Ingold substituents, diester malonates and ketals.

Reaction of alkylhypochlorites and xenon difluoride with cyclohexene

Shellhamer,Horney,Toth,Heasley

, p. 6903 - 6906 (2007/10/02)

Reactions of alkylhypochlorites and xenon difluoride with cyclohexene give primarily 1-chloro-2-fluorocyclohexanes via formation of a complex between xenon difluoride and the alkylhypochlorite.

Mechanistic aspects of the fluorination of cyclohexane and cyclohexene with acetyl hypofluorite in acetic acid

Visser, G. W. M.,Bakker, C. N. M.,Halteren, R. W. v.,Herscheld, J. D. M.,Brinkman, G. A.,Hoekstra, A.

, p. 214 - 219 (2007/10/02)

The reaction of acetyl hypofluorite in acetic acid with both cyclohexane and cyclohexene has been investigated.Analysis by GCMS and radio-HPLC, using (18)F as a tracer, revealed that apart from typical products expected from a radical reaction, several compounds originating from carbocationic intermediates were formed.On the basis of the observed products, a single-electrontransfer (SET) mechanism leading to an intermediate radical-cation is proposed.

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