226703-78-2 Usage
Uses
Used in Pharmaceutical Industry:
2-Oxazolidinone, 3-[(2S,3S)-3-hydroxy-2,4-dimethyl-1-oxo-4-pentenyl]-4-(phenylmethyl)-, (4S)is used as an intermediate in the synthesis of Jasplakinolide (J210700), a potent inhibitor of prostate and breast carcinoma cell proliferation. Its role in the development of 2-Oxazolidinone,
3-[(2S,3S)-3-hydroxy-2,4-dimethyl-1-oxo-4-pentenyl]-4-(phenylmethyl)-,
(4S)- makes it a valuable component in the fight against cancer, particularly in the treatment of prostate and breast cancers.
Used in Chemical Synthesis:
In addition to its application in the pharmaceutical industry, 2-Oxazolidinone, 3-[(2S,3S)-3-hydroxy-2,4-dimethyl-1-oxo-4-pentenyl]-4-(phenylmethyl)-, (4S)may also be used in various chemical synthesis processes. Its unique structure and functional groups can be utilized to create a range of other compounds with potential applications in different industries, such as materials science, agrochemicals, and more.
Check Digit Verification of cas no
The CAS Registry Mumber 226703-78-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,6,7,0 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 226703-78:
(8*2)+(7*2)+(6*6)+(5*7)+(4*0)+(3*3)+(2*7)+(1*8)=132
132 % 10 = 2
So 226703-78-2 is a valid CAS Registry Number.
226703-78-2Relevant academic research and scientific papers
Synthesis and biological evaluation of new jasplakinolide (jaspamide) analogs
Ghosh, Arun K.,Dawson, Zachary L.,Moon, Deuk Kyu,Bai, Ruoli,Hamel, Ernest
scheme or table, p. 5104 - 5107 (2010/10/04)
Synthesis and biological evaluation of jasplakinolide analogs are described. The synthesis of analogs utilized a diastereoselective syn-aldol reaction and an orthoester Claisen rearrangement as key steps. All synthetic analogs were evaluated for their abi
Synthesis of bioactive natural products by asymmetric syn-and anti-aldol reactions
Ghosh, Arun K.,Dawson, Zachary L.
scheme or table, p. 2992 - 3002 (2010/04/02)
The use of several variants of the asymmetric aldol reaction as key steps in the syntheses of bioactive target molecules is described. Georg Thieme Verlag Stuttgart.
Enantioselective total synthesis of (+)-jasplakinolide
Ghosh Deuk Kyu Moon, Arun K.
, p. 2425 - 2427 (2008/02/07)
An enantioselective total synthesis of (+)-jasplakinolide is described. The synthesis of the polyketide template utilized a diastereoselective syn-aldol, ortho-ester Claisen rearrangement followed by efficient conversion to a cyanide. The β-amino acid uni
