226879-40-9

Upstream product

• 226879-39-6 2-[(E)-6-(2-{Benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyl]-malonic acid dimethyl ester 
• 226879-36-3 [6-(2-{benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyloxy]-tert-butyl-diphenyl-silane 
• 226879-35-2 {2-[6-(tert-butyl-diphenyl-silanyloxy)-3-methyl-hex-3-enyl]-[1,3]dithian-2-yl}-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methanol 
• 226879-38-5 Methanesulfonic acid (E)-6-(2-{benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyl ester 
• 226879-37-4 (E)-6-(2-{Benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-en-1-ol 
• 226879-33-0 tert-butyl-(6-[1,3]dithian-2-yl-4-methyl-hex-3-enyloxy)-diphenyl-silane 
• 226879-31-8 7-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hept-4-enoic acid methyl ester 
• 226879-32-9 (E)-4-methyl-7-(tert-butyldiphenylsilyl)oxyhept-3-en-1-al 
• 226879-30-7 5-((tert-butyldiphenylsilyl)oxy)-2-methylpent-1-en-3-ol 

Downstream Products

• 226879-41-0 2-((E)-6-{2-[Benzyloxy-(5-chloromethyl-furan-2-yl)-methyl]-[1,3]dithian-2-yl}-4-methyl-hex-3-enyl)-malonic acid dimethyl ester 

Relevant academic research and scientific papers

Transannular Diels-Alder model studies on the total synthesis of chatancin. The furanophane approach. Part 1: Assembly of the acyclic substrates

Synthesis of three generations of model substrates with advancing similarity to chatancin are presented. In the first two generations, an Ireland-Claisen based six-step sequence supplied the trans-dienophile to be connected by dithiane chemistry to furfurals. In the third generation, a homogeraniol based dienophile aldehyde was coupled with a dilithiated 3- furoic acid. Subsequently, all three generations were concluded with similar functional group modifications as a preparation for a malonate-furyl chloride based macrocyclization.