226900-35-2

Basic information

• Product Name: diethyl 2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl phosphate
• Synonyms: diethyl 2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl phosphate
• CAS NO: 226900-35-2
• Molecular Weight: 363.394
• Mol File: 226900-35-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl phosphate(226900-35-2)
• EPA Substance Registry System: diethyl 2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl phosphate(226900-35-2)

Safety Data

• Hazardous Substances Data: 226900-35-2(Hazardous Substances Data)

Upstream product

• 197963-30-7 methyl N-(2,2-dimethyl-5-phenylpent-4-ynyl)glycinate 
• 197963-29-4 2,2-dimethyl-5-phenylpent-4-ynal 
• 3355-31-5 1-chloro-3-phenyl-2-propyne 
• 814-49-3 diethyl chlorophosphate 
• 197963-31-8 2,2-dimethyl-7-phenyl-2,3,5,6-tetrahydro-1H-pyrrolizin-6-one 

Downstream Products

• 133111-56-5 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine 

Relevant articles and documents

Synthetic studies towards ML-3000: A concise synthesis of this non- steroidal anti-inflammatory drug

ML-3000 was obtained from 1-chloro-3-phenyl-2-propyne in 8 steps with an overall yield of 19%. The key steps are a thermal acid-promoted bicyclization of an ω-acetylenic amino ester and a Suzuki cross-coupling reaction between a heteroaryl triflate and (4-chlorophenyl)boronic acid.