22692-80-4

Basic information

• Product Name: 1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE
• Synonyms: TOLANE 2-1;1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE;1-Ethyl-4-[2-(4-methylphenyl)-1-ethynyl]benzene;1-(4-Methylphenyl)-2-(4-ethylphenyl)ethyne;1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE: 99.5%;1-(4-ETHYL-4-[(P-TOLYL)ETHYLNYL]BENZENE;1-Ethyl-4-[(p-tolyl)ethynyl]benzene, 99+%;1-Ethyl-4-[(p-tolyl)ethynyl]benzene
• CAS NO: 22692-80-4
• Molecular Formula: C17H16
• Molecular Weight: 220.31
• Mol File: 22692-80-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 71-74°C
• Boiling Point: 135-136°C/1mm
• Flash Point: 135-136°C/1mm
• Appearance: /
• Density: 1.02 g/cm³
• Vapor Pressure: 0.000166mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE(22692-80-4)
• EPA Substance Registry System: 1-(4-ETHYLPHENYL)-2-(4-METHYLPHENYL)ACETYLENE(22692-80-4)

Safety Data

• Hazardous Substances Data: 22692-80-4(Hazardous Substances Data)

Usage

General Description

1-(4-Ethylphenyl)-2-(4-methylphenyl)acetylene is a chemical compound comprised of a variety of elements such as carbon, hydrogen, and a few other elements. It can be categorized under acetylenes, a group of compounds that contain a carbon-carbon triple bond. This particular compound has two phenyl groups attached to the acetylene structure - one phenyl group has an ethyl (2 carbon atoms) side chain while the other has a methyl (1 carbon atom) side chain. The physical and chemical properties, as well as the uses of this compound, depend on these structural features. However, there is not much information available publicly about the specific attributes and applications of this particular chemical compound.

InChI:InChI=1/C17H16/c1-3-15-8-10-17(11-9-15)13-12-16-6-4-14(2)5-7-16/h4-11H,3H2,1-2H3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 40307-11-7 1-ethyl-4-ethynylbenzene 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 1585-07-5 1-bromo-4-ethylbenzene 
• 766-97-2 4-n-methylphenylacetylene 
• 1345683-42-2 1-bromo-2-(4-ethylphenyl)acetylene 
• 112176-19-9 triisopropoxy(4-methylphenyl)titanium 
• 106-38-7 para-bromotoluene 
• 25309-64-2 4-ethyl-1-iodobenzene 

Downstream Products

• 28129-15-9 2-hydroxyethyl 4-methylbenzoate 
• 176665-20-6 (E)-1-ethyl-4-(4-methylstyryl)benzene 

Relevant articles and documents

An oxygen-bridged bimetallic [Cu-O-Se] catalyst for Sonogashira cross-coupling

Most non-palladium catalysts employed in Sonogashira cross-coupling work at high temperatures of 120-140 °C and with well-defined ligands. Palladium-based catalysts with bulky and electron-rich phosphine ligands generally show the best performance for the above-mentioned cross-coupling procedure. Herein, we report a new protocol for Csp-Csp2 Sonogashira cross-coupling between a terminal alkyne and aryl halide using the cheap and commercially available catalyst CuSeO3·2H2O. The title reaction proceeds using a variety of terminal alkynes, affording diaryl or aryl-alkyl acetylenes in high yields under mild conditions in the absence of ligands. Alkyl acetylenes, ethynylsilanes, and alkynols are efficiently coupled with aryl iodides and aryl bromides. The mechanism of the reaction was evaluated using computational DFT studies. To the best of our knowledge, this is the first example of the use of an oxygen-bridged copper-based bimetallic catalyst for Csp-Csp2 Sonogashira cross-coupling reactions under mild conditions. The reaction is palladium-free up to a limit of 0.2 ppm. This journal is

Visible-Light-Assisted Cobalt-2-(hydroxyimino)-1-phenylpropan-1-one Complex Catalyzed Pd/Cu-Free Sonogashira–Hagihara Cross-Coupling Reaction

An effective and inexpensive strategy for the Co(C9H9NO2)3 catalyzed Sonogashira–Hagihara cross-coupling reaction of aryl bromides containing electron-rich and electron-poor substituents with terminal alkynes wa

A novel silica-supported palladium catalyst for a copper-free Sonogashira coupling reaction

3-Aminopropyl functionalised silica gel may be readily transformed into a stable immobilised palladium catalyst. This catalyst was then successfully employed in a series of fast, copper-free Sonogashira coupling reactions. Georg Thieme Verlag Stuttgart.