226923-14-4Relevant academic research and scientific papers
Asymmetric synthesis of polyfunctionalized piperidines: Substitution at the C-4 position
Billon-Souquet, Florence,Martens, Thierry,Royer, Jacques
, p. 3731 - 3734 (2007/10/03)
The electrochemical bis-bromination of the chiral building block I followed by a dehydrobromination step allowed the preparation of a bromopiperideine 3. The stereoselective addition of nucleophiles onto this key intermediate permitted the synthesis of va
