226974-06-7

Upstream product

• 952-26-1 ethyl 5-phenylpyrrolidine-2-carboxylate 
• 830319-91-0 (5,5-dioxo-2,3S,5,9bS-tetrahydro-1H-5λ⁶-benzo[d]pyrrolo[1,2-b]isothiazol-3-yl)methanol 

Relevant academic research and scientific papers

Double reduction of cyclic aromatic sulfonamides: A novel method for the synthesis of 2- and 3-aryl-substituted cyclic amines

(Chemical Equation Presented) The facile double reduction of bicyclic aromatic sulfonamides was used to synthesize a variety of 2- and 3-aryl-substituted pyrrolidines and 2-phenylpiperidine. The method features a combined nitrogen protection and a traceless tether for the transposition of the aromatic moiety from nitrogen to carbon.

Convenient synthesis of C-aza-2,3-dideoxynucleosides

l-Aryl-l,2,3,4-tetradeoxy-l,4-imino-D-pentitols 5 and 9f are easily synthesized from TV-Boc-L-pyroglutamate 1 via a successive procedure involving regioselective ring-opening, recyclization with dehydration, stereoselective reduction, and reduction of the