226989-35-1

Basic information

• Product Name: 1-benzyl-1H-pyrazol-4-ol
• Synonyms: 1-benzyl-1H-pyrazol-4-ol;1-benzyl-4-hydroxy-1H-pyrazole
• CAS NO: 226989-35-1
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.1992
• EINECS: -0
• Mol File: 226989-35-1.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-benzyl-1H-pyrazol-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-1H-pyrazol-4-ol(226989-35-1)
• EPA Substance Registry System: 1-benzyl-1H-pyrazol-4-ol(226989-35-1)

Safety Data

• Hazardous Substances Data: 226989-35-1(Hazardous Substances Data)

Usage

General Description

1-benzyl-1H-pyrazol-4-ol is a chemical compound also known as 5413-59-7, an identifier that refers to its unique registration number in the Chemical Abstracts Service (CAS) Registry. 1-benzyl-1H-pyrazol-4-ol falls under the category of organic compounds, specifically those known as benzyl alcohols, suggesting its molecular structure comprises of a benzyl group and an alcohol group. It features a benzyl component, an aromatic ring, and a pyrazol group, which is a class of organic compounds containing a 5-membered aromatic ring made up of three carbon atoms and two nitrogen atoms. The term '4-ol' indicates the presence of an alcohol (hydroxyl) group on the fourth carbon of the pyrazol ring. While minimal information exists regarding its applications or potential harmful effects, like all chemicals, proper handling and safety protocols should be observed.

Upstream product

• 63874-95-3 1-benzyl-1H-pyrazole-4carboxaldehyde 
• 100-39-0 benzyl bromide 
• 761446-45-1 1-(phenylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 50877-42-4 1-benzyl-4-iodo-1H-pyrazole 

Downstream Products

• 1218994-43-4 1-benzyl-4-methoxy-1H-pyrazole 
• 1326316-19-1 4-allyloxy-1-benzyl-1H-pyrazole 
• 1326316-24-8 C₁₃H₁₄N₂O 
• 1326316-31-7 3,5-diallyl-2-benzyl-4-hydroxy-2H-pyrazole 
• 226989-41-9 (S)1-Benzyl-4-(3-[N-(3-[4-(4-carbamoylphenoxy)phenyl]-1,1-dimethylpropyl)amino]-2-hydroxypropoxy)pyrazole 

Relevant articles and documents

Regioselective palladium-catalyzed C–H arylation of 4-alkoxy and 4-thioalkyl pyrazoles

A methodology for the palladium-catalyzed regioselective C–H arylation of electron rich pyrazoles has been developed. New ligands and mild conditions (70–90 °C) have been identified for this transformation. An intramolecular application of the methodology provided a novel synthetic route for the regioselective synthesis of 1,5-dihydroisochromeno[4,3-c]pyrazoles and 1,5-dihydroisothiochromeno[4,3-c]pyrazoles.

9H-PYRROLO-DIPYRIDINE DERIVATIVES

The invention relates to 9H-pyrrolo-dipyridine derivatives of formula I, processes for preparing them, pharmaceutical compositions containing them and their use as radiopharmaceuticals in particular as imaging agents for the detection of Tau aggregates.

HISTONE DEMETHYLASE INHIBITORS

The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like