226993-07-3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 181020-92-8 3-(2'-phenylethyl)-pent-4-yn-1-ol 

Downstream Products

• 226993-31-3 methyl 2-acetyl-5-(2'-phenyl-ethyl)-7-trimethylsilyl-hepta-6-ynoate 
• 226993-43-7 methyl 2-acetyl-5-(2'-phenyl-ethyl)-hepta-6-ynoate 
• 226993-19-7 1-bromo-3-(2'-phenylethyl)-5-trimethylsilyl-pent-4-yne 

Relevant academic research and scientific papers

Cobalt-mediated cycloisomerization of δ-substituted ε-acetylenic β- ketoesters construction of angular triquinane by a sequence ene/Pauson-Khand reactions

The preparation of δ-substituted ε-acetylenic β-ketoesters is fully described. Their cobalt-mediated Conia-ene reactions led to variously functionalized methylenecyclopentanes in high yields land with a moderate control of the 1,4 diastereoselectivity. A sequence involving the cobalt- mediated ene and Pauson-Khand reactions is presented and allowed the construction of the angular triquinane framework.