226993-47-1Relevant articles and documents
Cobalt-mediated cycloisomerization of δ-substituted ε-acetylenic β- ketoesters construction of angular triquinane by a sequence ene/Pauson-Khand reactions
Renaud, Jean-Luc,Aubert, Corinne,Malacria, Max
, p. 5113 - 5128 (2007/10/03)
The preparation of δ-substituted ε-acetylenic β-ketoesters is fully described. Their cobalt-mediated Conia-ene reactions led to variously functionalized methylenecyclopentanes in high yields land with a moderate control of the 1,4 diastereoselectivity. A sequence involving the cobalt- mediated ene and Pauson-Khand reactions is presented and allowed the construction of the angular triquinane framework.