226993-01-7

Upstream product

• 75-21-8 oxirane 
• 119405-97-9 4-phenyl-1,1-dibromo-1-butene 
• 104-53-0 3-phenyl-propionaldehyde 
• 100-39-0 benzyl bromide 
• 68975-07-5 3-benzyltetrahydrofuran-2-one 

Downstream Products

• 226993-37-9 tert-butyl 2-acetyl-5-phenylmethyl-7-trimethylsilyl-hepta-6-ynoate 
• 226993-29-9 methyl 2-acetyl-5-phenylmethyl-7-trimethylsilyl-hepta-6-ynoate 
• 226993-47-1 tert-butyl 2-acetyl-5-phenylmethyl-hepta-6-ynoate 
• 226993-17-5 1-bromo-3-phenylmethyl-5-trimethylsilyl-pent-4-yne 
• 1644306-22-8 (4-cyclopropylidene-2-ethynylhept-5-yn-1-yl)benzene 
• 1644306-04-6 6-benzylocta-2,7-diyn-4-one 
• 1644306-09-1 C₁₅H₁₆O 
• 1644306-08-0 C₁₂H₁₂O 
• 226993-06-2 3-phenylmethyl-5-trimethylsilyl-pent-4-yn-1-ol 

Relevant academic research and scientific papers

Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters

A unique method to affect intramolecular aminooxygenation and dioxygenation of allenols and allenylsulfonamides is described. These operationally simple reactions occur under neutral or basic conditions where copper(II) carboxylates serve as reaction promoter, oxidant, and carboxylate source. Moderate to high yields of heterocycle-functionalized vinyl carboxylate esters are formed with moderate to high levels of diastereoselectivity. Such vinyl carboxylate esters could serve as precursors to α-amino and α-oxy ketones and derivatives thereof.

Cobalt-mediated cycloisomerization of δ-substituted ε-acetylenic β- ketoesters construction of angular triquinane by a sequence ene/Pauson-Khand reactions

The preparation of δ-substituted ε-acetylenic β-ketoesters is fully described. Their cobalt-mediated Conia-ene reactions led to variously functionalized methylenecyclopentanes in high yields land with a moderate control of the 1,4 diastereoselectivity. A sequence involving the cobalt- mediated ene and Pauson-Khand reactions is presented and allowed the construction of the angular triquinane framework.