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226998-04-5

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226998-04-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 226998-04-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,6,9,9 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 226998-04:
(8*2)+(7*2)+(6*6)+(5*9)+(4*9)+(3*8)+(2*0)+(1*4)=175
175 % 10 = 5
So 226998-04-5 is a valid CAS Registry Number.

226998-04-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-N-(2-methylbenzyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

1.2 Other means of identification

Product number -
Other names (R)-5,5-Dimethyl-thiazolidine-4-carboxylic acid 2-methyl-benzylamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:226998-04-5 SDS

226998-04-5Relevant articles and documents

Truncation and non-natural amino acid substitution studies on HTLV-I protease hexapeptidic inhibitors

Nguyen, Jeffrey-Tri,Zhang, Meihui,Kumada, Henri-Obadja,Itami, Ayako,Nishiyama, Keiji,Kimura, Tooru,Cheng, Maosheng,Hayashi, Yoshio,Kiso, Yoshiaki

, p. 366 - 370 (2008/09/18)

The culprit behind adult T-cell leukemia, myelopathy/tropical paraparesis, and a plethora of inflammatory diseases is the human T-cell leukemia virus type 1 (HTLV-I). We recently unveiled a potent hexapeptidic HTLV-I protease inhibitor, KNI-10166, compose

Structure-activity and structure-metabolism relationships of HIV protease inhibitors containing the 3-hydroxy-2-methylbenzoyl-allophenylnorstatine structure

Mimoto, Tsutomu,Terashima, Keisuke,Nojima, Satoshi,Takaku, Haruo,Nakayama, Mitsunobu,Shintani, Makoto,Yamaoka, Takashi,Hayashi, Hideya

, p. 281 - 293 (2007/10/03)

A series of peptidomimetic human immunodeficiency virus (HIV) protease inhibitors containing substituted allophenylnorstatine [Apns: (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid] were designed and synthesized. From the structure-metabolism relationship of this type of HIV protease inhibitors, the compounds having para substitution of the phenyl ring of Apns and/or 2,6-disubstitution of the P2′ benzylamine were found to be able to avoid the P2 phenol glucuronidation that occurs with SM-319777 (formerly named JE-2147, KNI-764); one of the main metabolic pathways of SM-319777. These new analogues, such as SM-322377, had more desirable pharmacokinetic profiles and more potent antiviral activity against not only wild type HIV-1 but also the multi-drug-resistant HIV-1 than SM-319777.

Tripeptide compounds and anti-AIDS medicine

-

, (2008/06/13)

A novel tripeptide compound represented by the following general formula (I) exhibiting superior HIV protease inhibition activity, and an anti-AIDS medicine comprising this compound as an effective component and a pharmaceutically acceptable salt thereof.

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