22707-48-8

Basic information

• Product Name: p-Trifluormethylphenyl-tert.butyl-methyl-carbinol
• Synonyms: p-Trifluormethylphenyl-tert.butyl-methyl-carbinol
• CAS NO: 22707-48-8
• Molecular Weight: 246.273
• Mol File: 22707-48-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: p-Trifluormethylphenyl-tert.butyl-methyl-carbinol(CAS DataBase Reference)
• NIST Chemistry Reference: p-Trifluormethylphenyl-tert.butyl-methyl-carbinol(22707-48-8)
• EPA Substance Registry System: p-Trifluormethylphenyl-tert.butyl-methyl-carbinol(22707-48-8)

Safety Data

• Hazardous Substances Data: 22707-48-8(Hazardous Substances Data)

Upstream product

• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 677-22-5 tert-butylmagnesium chloride 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 119449-34-2 3,3-dimethyl-2-(4'-trifluoromethylphenyl)-2-butyl p-nitrobenzoate 
• 22666-57-5 p-Trifluormethyl-tert-butyl-methyl-carbinylchlorid 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 

Downstream Products

• 22666-57-5 p-Trifluormethyl-tert-butyl-methyl-carbinylchlorid 
• 22666-67-7 1-(3,3-dimethylbut-1-en-2-yl)-4-(trifluoromethyl)benzene 

Relevant articles and documents

Substituent effects on the solvolysis rates and gas phase stabilities of 1,2,2-trimethyl-1-phenylpropyl and 1,2,2-trimethyl-1-(2-methylphenyl)propyl systems

Substituent effects on the solvolysis rates of 1,2,2-trimethyl-1- phenylpropyl chlorides in 80% (v/v) aq acetone at 45 °C and 1,2,2-trimethyl- 1-(2-methylphenyl)propyl p-nitrobenzoates in 50% (v/v) aq ethanol at 75 °C were correlated with the Yukawa-Tsuno

Solvolysis of 2-Aryl-3,3-dimethyl-2-butyl p-Nitrobenzoates. β-Deuterium Kinetic Isotope Effects and the Linear Free Energy Relationships

Solvolysis of 2-aryl-3,3-dimethyl-2-butyl p-nitrobenzoates (4a-4d) and the 1,1,1-trideuterio derivatives (5a,5b,5c) in HFIP exhibited a high kinetic isotope effect, k(CH3)/k(CD3) = 1.90 at 60 deg C for the deactivating substrates 4c vs 5c.This effect decreased significantly with increasing electron releasing of the substituent on the aryl ring.Hammett-Brown treatment of the rate data for 4 yielded excellent linear relationships (r = 0.999) with ρ+ = -3.48.It is evident that the contribution of the α-methyl group to the stabilization of the cationic transition state is not constant.The approximation in the linear free energy relationship is discussed.