227078-24-2Relevant articles and documents
Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone
Sui, Guoqing,Lv, Qingyun,Song, Xiaoqing,Guo, Huihui,Dai, Jiatong,Ren, Li,Lee, Chi-Sing,Zhou, Wenming,Hao, Hong-Dong
supporting information, p. 15793 - 15796 (2019/10/19)
A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.
Selective transformations of carbonyl functions in the presence of α,β-unsaturated ketones: Concise asymmetric total synthesis of decytospolides A and B
Yahata, Kenzo,Minami, Masaki,Watanabe, Kei,Fujioka, Hiromichi
supporting information, p. 3680 - 3683 (2014/08/05)
Enones selectively react with a combination of PPh3 and TMSOTf to produce phosphonium silyl enol ethers, which work as protective groups of enones during the reduction of other carbonyl functions and can be easily deprotected to regenerate parent enones at workup. Furthermore, the first ketone selective alkylations in the presence of enones were also accomplished. This in situ protection method was applied to concise asymmetric total syntheses of decytospolides A and B.
New scavenger resin for the reversible linking and monoprotection of functionalized aromatic aldehydes
Zhu, Mingzhao,Ruijter, Eelco,Wessjohann, Ludger A.
, p. 3921 - 3924 (2007/10/03)
(Chemical Equation Presented) Polymer-supported benzylhydrazines were synthesized using poly(ethylene glycol) acrylamide (PEGA) resin. They can be used to scavenge electrophiles reactive with hydrazine. Especially aromatic aldehydes can be captured select
