227084-59-5Relevant academic research and scientific papers
CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF
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Page/Page column 97; 98, (2010/06/19)
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
METHODS AND COMPOUNDS FOR PREPARING CC-1065 ANALOGS
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Page/Page column 30; Fig.2, (2010/11/27)
A method of forming a CBI CC- 1065 analog utilizes NH2 as a starting material, where R3 is H or alkyl and R6 is H, substituted or unsubstituted lower alkyl, cyano, or alkoxy. Intermediates (I) are used and are claimed.
